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Chicago State vs. Loyola Chicago prediction: Loyola Chicago favored to win men's college basketball matchup [12/14/2025]
Get Chicago State vs Loyola Chicago predictions for college basketball Sunday.

Loyola Chicago will face Chicago State in men's college basketball action at Joseph J. Gentile Arena on Sunday, beginning at 5:00PM ET.
Based on updated simulations, Dimers' advanced college basketball model projects Loyola Chicago as the most likely winner of the Chicago State vs. Loyola Chicago game.
This article offers further insights into Sunday's matchup, including an expanded look at the predicted score, best bets and picks.
Chicago State vs. Loyola Chicago prediction: Who will win and cover?
Using innovative machine learning and data analysis, we have simulated the outcome of Sunday's NCAA basketball matchup between Chicago State and Loyola Chicago 10,000 times as part of our men's college basketball predictions coverage.
Our leading predictive model gives Loyola Chicago a 92% chance of defeating Chicago State. Our predicted final score has Loyola Chicago winning 78-63.
According to our model, Loyola Chicago (-14.5) has a 53% chance of covering the spread, while the over/under total of 140.5 points has a 52% chance of going over.
Chicago State vs. Loyola Chicago odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Chicago State | Loyola Chicago |
|---|---|---|
| Spread | +14.5 (-115) | -14.5 (-105) |
| Moneyline | +850 | -1400 |
| Total | o140.5 (-110) | u140.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Chicago State vs. Loyola Chicago picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Loyola Chicago -14.5 | -105 |
| Moneyline | Loyola Chicago | -1400 |
| Total | Over 140.5 | -110 |
According to our men's college basketball best bets, the top play to make on this game is Loyola Chicago -14.5 at the spread.
Chicago State vs. Loyola Chicago game-day updates and essential details
Sunday's men's college basketball action between Loyola Chicago and Chicago State at Joseph J. Gentile Arena is scheduled to start at 5:00PM ET.
- Who: Chicago State vs. Loyola Chicago
- Date: Sunday, December 14, 2025
- Time: 5:00PM ET/2:00PM PT
- Venue: Joseph J. Gentile Arena
Conclusion
We predict Loyola Chicago, with a 92% win probability, will likely beat Chicago State on Sunday.
AI and automation have enhanced this article to quickly deliver accurate Chicago State vs. Loyola Chicago insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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