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Chicago State vs. Loyola Chicago prediction: Loyola Chicago favored to win men's college basketball matchup [12/14/2025]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Chicago State vs Loyola Chicago predictions for college basketball Sunday.
Loyola Chicago and Chicago State will meet in men's college basketball action at Joseph J. Gentile Arena on Sunday, starting at 5:00PM ET.
Based on the latest simulations, Dimers' advanced college basketball model projects Loyola Chicago as the most likely winner of the Chicago State vs. Loyola Chicago game.
This article offers further insights into Sunday's matchup, including an expanded look at the predicted score, best bets and picks.
Chicago State vs. Loyola Chicago prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the outcome of Sunday's NCAA basketball game between Chicago State and Loyola Chicago 10,000 times as part of our men's college basketball predictions coverage.
Our famous predictive model gives Loyola Chicago a 93% chance of defeating Chicago State. Our predicted final score has Loyola Chicago winning 78-63.
According to our model, Loyola Chicago (-15.5) has a 52% chance of covering the spread, while the 140.5-point over/under has a 53% chance of going over.
Chicago State vs. Loyola Chicago odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Chicago State | Loyola Chicago |
|---|---|---|
| Spread | +15.5 (-110) | -15.5 (-105) |
| Moneyline | +920 | -1600 |
| Total | o140.5 (-110) | u140.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Chicago State vs. Loyola Chicago picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Loyola Chicago -15.5 | -105 |
| Moneyline | Loyola Chicago | -1600 |
| Total | Over 140.5 | -110 |
According to our men's college basketball best bets, the top play to make on this game is Over 140.5 total points.
Chicago State vs. Loyola Chicago game-day updates and essential details
Sunday's men's college basketball matchup between Loyola Chicago and Chicago State at Joseph J. Gentile Arena is scheduled to commence at 5:00PM ET.
- Who: Chicago State vs. Loyola Chicago
- Date: Sunday, December 14, 2025
- Time: 5:00PM ET/2:00PM PT
- Venue: Joseph J. Gentile Arena
Conclusion
We predict Loyola Chicago, with a 93% win probability, will likely beat Chicago State on Sunday.
AI and automation have enhanced this article to quickly deliver accurate Chicago State vs. Loyola Chicago insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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