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Chicago State vs. Indiana prediction: Why Indiana is favored to win men's college basketball matchup [12/20/2025]

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Written by Dave Garofolo

Get Chicago State vs Indiana predictions for college basketball Saturday.

Chicago State-Indiana Predictions and Game Preview.
Chicago State vs. Indiana men's college basketball prediction for Saturday, December 20, 2025.

Indiana will take on Chicago State in men's college basketball action at Simon Skjodt Assembly Hall on Saturday, beginning at 1:00 PM ET.

Based on the latest simulation results, Dimers' proven college basketball model projects Indiana as the most likely winner of the Chicago State vs. Indiana game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Chicago State vs. Indiana prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Saturday's NCAA basketball game between Chicago State and Indiana 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives Indiana a 99% chance of defeating Chicago State. Our predicted final score has Indiana winning 90-60.

According to our model, Chicago State (+38.5) has a 60% chance of covering the spread, while the 151.5-point over/under has an equal 50-50 chance of hitting.

 

Chicago State vs. Indiana odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type Chicago State Indiana
Spread +38.5 (-105) -38.5 (-110)
Moneyline +8000 -100000
Total o151.5 (-110) u151.5 (-105)

All odds are correct at the time of publication and are subject to change.

Chicago State vs. Indiana picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Chicago State +38.5 -105
Moneyline Chicago State +8000
Total Under 151.5 -105

According to our best men's college basketball bets, the top play to make on this game is Chicago State +38.5 at the spread.

 

Chicago State vs. Indiana game-day updates and essential details

Saturday's men's college basketball game between Indiana and Chicago State at Simon Skjodt Assembly Hall is scheduled to begin at 1:00 PM ET.

  • Who: Chicago State vs. Indiana
  • Date: Saturday, December 20, 2025
  • Time: 1:00 PM ET/10:00AM PT
  • Venue: Simon Skjodt Assembly Hall

Conclusion

We predict Indiana, with a 99% win probability, will likely beat Chicago State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Chicago State vs. Indiana insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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