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Chicago State vs. Illinois State prediction: Why Illinois State is favored to win men's college basketball matchup [12/6/2025]

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Written by Dave Garofolo

Get Chicago State vs Illinois State predictions for college basketball Saturday.

Chicago State-Illinois State Predictions and Game Preview.
Chicago State vs. Illinois State men's college basketball prediction for Saturday, December 6, 2025.

Illinois State will square off with Chicago State in men's college basketball action at CEFCU Arena on Saturday, starting at 8:00PM ET.

Based on the latest simulation results, Dimers' proven college basketball model predicts Illinois State as the most likely winner of the Chicago State vs. Illinois State game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Chicago State vs. Illinois State prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Saturday's NCAA basketball matchup between Chicago State and Illinois State 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Illinois State a 96% chance of defeating Chicago State. Our predicted final score has Illinois State winning 85-64.

According to our model, Chicago State (+21.5) has a 52% chance of covering the spread, while the over/under total of 145.5 points has a 55% chance of going over.

 

Chicago State vs. Illinois State odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type Chicago State Illinois State
Spread +21.5 (-110) -21.5 (-108)
Moneyline +1800 -5000
Total o145.5 (-105) u145.5 (-112)

All odds are correct at the time of publication and are subject to change.

Chicago State vs. Illinois State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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