Chicago State vs. Illinois State prediction: Why Illinois State is favored to win men's college basketball matchup [12/6/2025]

Illinois State will take on Chicago State in men's college basketball action at CEFCU Arena on Saturday, starting at 8:00PM ET.

Based on the latest simulations, Dimers' advanced college basketball model predicts Illinois State as the most likely winner of the Chicago State vs. Illinois State game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Chicago State vs. Illinois State prediction: Who will win and cover?

Using powerful machine learning and data analysis, we have simulated the outcome of Saturday's NCAA basketball matchup between Chicago State and Illinois State 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Illinois State a 97% chance of beating Chicago State. Our predicted final score has Illinois State winning 86-64.

According to our model, Illinois State (-20.5) has a 52% chance of covering the spread, while the 144.5-point over/under has a 57% chance of going over.

Chicago State vs. Illinois State odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Chicago State vs. Illinois State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our men's college basketball best bets, the top play to make on this game is Over 144.5 total points.

Chicago State vs. Illinois State game-day updates and essential details

Saturday's men's college basketball game between Illinois State and Chicago State at CEFCU Arena is scheduled to commence at 8:00PM ET.

• Who: Chicago State vs. Illinois State
• Date: Saturday, December 6, 2025
• Time: 8:00PM ET/5:00PM PT
• Venue: CEFCU Arena

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Conclusion

We predict Illinois State, with a 97% win probability, will likely beat Chicago State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Chicago State vs. Illinois State insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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