Chicago Cubs vs. Arizona Diamondbacks Prediction, Odds, MLB Picks [4/17/2024]

Chicago Cubs vs. Arizona Diamondbacks Prediction, Odds, MLB Picks [4/17/2024]

MLB action continues on Wednesday at 3:40PM ET as the Chicago Cubs square off with the Arizona Diamondbacks at Chase Field.

The Diamondbacks will start Brandon Pfaadt (1-0, 6.48 ERA), while the Cubs will counter with Jordan Wicks (0-2, 5.68 ERA).'s comprehensive preview of Wednesday's Cubs vs. Diamondbacks matchup includes our prediction, picks and the latest betting odds.

THIS WEEK ONLY: Use the code DIMERSMLB at checkout to get 20% off an annual Dimers Pro subscription. That's less than $17 a month. Join now and get instant access to all our MLB insights.

Cubs vs. Diamondbacks Prediction: Who Will Win, Cover the Run Line

We have used trusted machine learning and data to simulate the result of Wednesday's MLB game between the Cubs and Diamondbacks 10,000 times, in keeping with our coverage of MLB picks.

Our leading predictive analytics model currently gives the Diamondbacks a 53% chance of defeating the Cubs.

According to our model, the Cubs (+1.5) have a 65% chance of covering the run line, while the 9-run over/under has a 51% chance of going over.

Cubs vs. Diamondbacks Odds [4/17/2024]

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type Cubs Diamondbacks
Run Line +1.5 (-185) -1.5 (+164)
Moneyline +110 -130
Total o9 (-105) u9 (-110)

All odds are correct at the time of publication and are subject to change.

Cubs vs. Diamondbacks Picks

At Dimers, our predictions, paired with the best odds, reveal the top betting picks to make on every game, including Cubs vs. Diamondbacks. Our MLB best bets are based on expert modeling and analysis, as you can see.

Dimers Pro unlocks +EV bets daily. Join Dimers Pro now to get exclusive access to hundreds of data-driven bets daily across thousands of games, including the ability to see any potential picks for this matchup.

EXCLUSIVE: Save $50 on an annual subscription for a limited time only by using code DIMERSMLB at the Dimers Pro checkout.


Cubs vs. Diamondbacks Game Information

Wednesday's MLB game between the Diamondbacks and Cubs at Chase Field is scheduled to commence at 3:40PM ET.


Our full betting coverage of the Cubs vs. Diamondbacks includes pregame predictions, betting picks and live win probabilities.

Calling Our Shot: Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the free picks featured below.


We predict the Diamondbacks, with a 53% win probability, will likely beat the Cubs on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Cubs vs. Diamondbacks insights, with human oversight ensuring high editorial quality. Our predictions are based on current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee.

More on MLB

Stay informed with the latest MLB news and our data-led MLB picks and parlays all season long. Plus, our World Series odds give you the latest probabilities and the best available odds on the World Series, American League, National League, and each division.

Dave Garofolo
Content Producer

Dave Garofolo, a seasoned fantasy sports and betting enthusiast with a special affection for MLB and NFL, uses his deep knowledge to craft game previews for the NBA, MLB, and NFL. He also brings his expertise to the golf world with tournament previews and parlays for the PGA TOUR and major golf tournaments. Additionally, Dave offers valuable props for NBA, MLB, NHL, and NCAAM basketball, along with best bets for MLB, NHL, and NCAAM. 

When not delving into the world of sports, Dave is an avid advocate for New Haven pizza, enjoys reading comic books, gardening, and spending time with his cats. His broad interests and detailed sports insights ensure that his contributions are both engaging and informative.

On the socials
More from Dimers
About Dimers
icon 22,000+
Events covered per year
icon 8,000,000+
Our partners