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Charleston vs. Northern Kentucky prediction: Northern Kentucky favored to win men's college basketball matchup [12/21/2025]

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Written by Jason Bevilacqua

Get Charleston vs Northern Kentucky predictions for college basketball Sunday.

Charleston-Northern Kentucky Predictions and Game Preview.
Charleston vs. Northern Kentucky men's college basketball prediction for Sunday, December 21, 2025.

Northern Kentucky and Charleston are scheduled to meet in men's college basketball action at Truist Arena on Sunday, starting at 12:00 PM ET.

Based on the latest simulation results, Dimers' proven college basketball model predicts Northern Kentucky as the most likely winner of the Charleston vs. Northern Kentucky game.

This article offers an expanded analysis of Sunday's matchup, including an expanded look at the predicted score, best bets and picks.

Charleston vs. Northern Kentucky prediction: Who will win and cover?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Sunday's NCAA basketball matchup between Charleston and Northern Kentucky 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Northern Kentucky a 69% chance of beating Charleston. Our predicted final score has Northern Kentucky winning 78-73.

According to our model, Northern Kentucky (-4.5) has a 55% chance of covering the spread, while the 153.5-point over/under has a 54% chance of going over.

 

Charleston vs. Northern Kentucky odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

Bet Type Charleston Northern Kentucky
Spread +4.5 (-105) -4.5 (-105)
Moneyline +195 -192
Total o153.5 (-110) u153.5 (-110)

All odds are correct at the time of publication and are subject to change.

Charleston vs. Northern Kentucky picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Northern Kentucky -4.5 -105
Moneyline Northern Kentucky -192
Total Over 153.5 -110

According to our men's college basketball best bets, the top play to make on this game is Northern Kentucky -4.5 at the spread.

 

Charleston vs. Northern Kentucky game-day updates and essential details

Sunday's men's college basketball matchup between Northern Kentucky and Charleston at Truist Arena is scheduled to commence at 12:00 PM ET.

  • Who: Charleston vs. Northern Kentucky
  • Date: Sunday, December 21, 2025
  • Time: 12:00 PM ET/9:00AM PT
  • Venue: Truist Arena

Conclusion

We predict Northern Kentucky, with a 69% win probability, will likely beat Charleston on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Charleston vs. Northern Kentucky insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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