Cardinals vs. Reds Prediction and Odds - Apr 23, 2022

MLB action continues on Saturday at 4:10PM ET as the St Louis Cardinals lock horns with the Cincinnati Reds at Great American Ball Park.

Tyler Mahle (1-1, 7.82 ERA) will start on the mound for the Reds, while the Cardinals will counter with Dakota Hudson (0-1, 7.71 ERA).

Dimers' best betting picks for Cardinals vs. Reds, as well as game predictions and best odds, are detailed below.

Who will win Cardinals vs. Reds?

Based on cutting-edge machine learning and data, Dimers.com has simulated Saturday's Cardinals-Reds MLB matchup 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, gives the Cardinals a 57% chance of beating the Reds.

More: Cardinals vs. Reds Simulated 10K Times

Cardinals vs. Reds Odds

• Run Line: Reds +1.5 (-175), Cardinals -1.5 (+155)
• Moneyline: Reds -115, Cardinals +100
• Total: Over/Under 8.5 (+100/-108)

Run Line, Moneyline and Over/Under

The Reds are listed as +1.5 underdogs against the Cardinals, with -175 at Caesars Sportsbook the best odds currently available.

For the favored Cardinals (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +155.

Caesars Sportsbook currently has the best moneyline odds for the Reds at -115, which means you can risk $115 to win $100, for a total payout of $215, if they get the W.

Meanwhile, DraftKings Sportsbook currently has the best moneyline odds for the Cardinals at +100, where you can risk $100 to win $100, for a total payout of $200, if they come out on top.

The Over/Under sits at 8.5 with Caesars Sportsbook, which currently has the best odds for the Over at +100, while FanDuel Sportsbook currently has the best odds for the Under at -108.

As always, make sure you check the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Reds (+1.5) are a 62% chance of covering the run line, while the 8.5-run Over/Under is a 51% chance of going Over.

More: Best Bets Today for All Major Sports

Best Bets for Cardinals vs. Reds

• Run Line: Cardinals -1.5 @ +155 via DraftKings Sportsbook
• Moneyline: Cardinals @ +100 via DraftKings Sportsbook (57% probability) 🔥
• Total: Over 8.5 @ +100 via Caesars Sportsbook (51% probability)

If you see a 🔥, that means you've found one of our best free picks of the day across any sport.

Dimers' best bets are based on detailed simulations and wagering intelligence to serve you the best possible plays every day of the year.

Although the Reds are more likely to cover the run line, our best bet of Cardinals -1.5 is based on the expectation of that happening, according to DimersBOT, and the best odds available.

Cardinals vs. Reds Betting Guide

Use our dynamic widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for St Louis vs. Cincinnati, and click or tap on See Matchup for more.

Dimers has full betting coverage of Saturday's Cardinals-Reds matchup, including pregame predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so check this article for the latest betting analysis ahead of Cardinals vs. Reds on Saturday April 23, 2022.

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Cardinals vs. Reds 2022 Game Info

When do the Reds play the Cardinals?

• Date: Saturday April 23, 2022
• Time: 4:10PM ET / 1:10PM PT
• Venue: Great American Ball Park

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What other MLB games are on today?

The Cardinals and Reds aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and top bets for every single MLB matchup in our MLB Bet Hub section.

Not only do we provide with you great predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

Lastly, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.