Cardinals vs. Marlins Prediction and Odds - Apr 21, 2022

The Miami Marlins square off with the St Louis Cardinals in MLB action at loanDepot park on Thursday, beginning at 6:40PM ET.

Pablo López (1-0, 0.87 ERA) will be on the bump for the Marlins, up against Jordan Hicks (1-0, 0.00 ERA) for the Cardinals.

Dimers' top betting picks for Cardinals vs. Marlins, plus game predictions and best odds, are featured below.

Who will win Cardinals vs. Marlins?

Based on trusted computer power and data, Dimers.com has simulated Thursday's Cardinals-Marlins MLB game 10,000 times.

Dimers' renowned predictive analytics model, DimersBOT, gives the Marlins a 52% chance of defeating the Cardinals.

More: Free Betting Analysis for Cardinals vs. Marlins

Cardinals vs. Marlins Current Odds

• Run Line: Marlins -1.5 (+155), Cardinals +1.5 (-175)
• Moneyline: Marlins -130, Cardinals +115
• Total: Over/Under 7.5 (+100/-120)

Run Line, Moneyline and Over/Under

The Marlins are listed as -1.5 favorites against the Cardinals, with +155 at BetMGM the best odds currently available.

For the underdog Cardinals (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on the market at -175.

Caesars Sportsbook currently has the best moneyline odds for the Marlins at -130, which means you can risk $130 to win $100, for a total payout of $230, if they get the W.

On the other hand, DraftKings Sportsbook currently has the best moneyline odds for the Cardinals at +115, where you can bet $100 to profit $115, earning a total payout of $215, if they win.

The Over/Under for total runs scored is set at 7.5 with BetMGM, which currently has the best odds for the Over at +100, as well as the best odds for the Under at -120.

As always, make sure you check all the sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Cardinals (+1.5) are a 65% chance of covering the run line, while the 7.5-run Over/Under is a 51% chance of going Over.

More: Today's Best Bets for All Major Sports

Best Bets for Cardinals vs. Marlins

• Run Line: Cardinals +1.5 @ -175 via Caesars Sportsbook (65% probability)
• Moneyline: Cardinals @ +115 via DraftKings Sportsbook (1.2% edge)
• Total: Over 7.5 @ +100 via BetMGM (51% probability)

Dimers' best bets are based on detailed simulations and wagering intelligence to help you make smarter decisions with the legal sportsbooks in your state.

While the Marlins are more likely to win the game, according to DimersBOT, taking the Cardinals moneyline is the best option because of the 1.2% edge identified when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen on Dimers is crucial to achieving long-term profitability as a sports bettor.

Cardinals vs. Marlins Betting Guide

Use our dynamic widget below to see the latest Moneyline, Over/Under and Run Line probabilities and odds for St Louis vs. Miami, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Thursday's Cardinals-Marlins matchup, including pregame predictions, best betting picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so keep an eye on this article for any changes to our betting analysis before Cardinals vs. Marlins on Thursday April 21, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Cardinals vs. Marlins 2022 Game Info

When do the Marlins play the Cardinals?

• Date: Thursday April 21, 2022
• Time: 6:40PM ET / 3:40PM PT
• Venue: loanDepot park

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What MLB games are on today?

The Cardinals and Marlins aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and best bets for each and every MLB matchup via our MLB Predictions page.

Not only do we provide with you first-class predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Check it out now!

Lastly, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.