Cardinals vs. Marlins Prediction and Odds - Apr 20, 2022

The Miami Marlins and St Louis Cardinals meet in MLB at loanDepot park on Wednesday, starting at 6:40PM EDT.

Sandy Alcantara (1-0, 3.18 ERA) will get the ball for the Marlins, up against Miles Mikolas (1-0, 2.61 ERA) for the Cardinals.

Dimers' free betting picks for Cardinals vs. Marlins, plus game predictions and best odds, are featured below.

Who will win Cardinals vs. Marlins?

Using high-tech computer power and data, Dimers.com has simulated Wednesday's Cardinals-Marlins MLB matchup 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Marlins a 54% chance of winning against the Cardinals.

More: Cardinals vs. Marlins Simulated 10,000 Times

Cardinals vs. Marlins Game Odds

• Run Line: Marlins -1.5 (+150), Cardinals +1.5 (-165)
• Moneyline: Marlins -135, Cardinals +122
• Total: Over/Under 7.5 (-110/-105)

Run Line, Moneyline and Over/Under

The Marlins are listed as -1.5 favorites against the Cardinals, with +150 at DraftKings Sportsbook the best odds currently available.

For the underdog Cardinals (+1.5) to cover the run line, BetMGM has the best odds currently on offer at -165.

Caesars Sportsbook currently has the best moneyline odds for the Marlins at -135, which means you can risk $135 to win $100, for a total payout of $235, if they get the W.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for the Cardinals at +122, where you can bet $100 to profit $122, earning a total payout of $222, if they win.

The Over/Under is set at 7.5 with BetMGM, which currently has the best odds for the Over at -110, while PointsBet currently has the best odds for the Under at -105.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Cardinals (+1.5) are a 63% chance of covering the run line, while the Over/Under total of 7.5 runs is a 54% chance of going Over.

More: Best Bets Today for All Major Sports

Best Bets for Cardinals vs. Marlins

• Run Line: Cardinals +1.5 @ -165 via BetMGM (63% probability)
• Moneyline: Cardinals @ +122 via FanDuel Sportsbook (0.9% edge)
• Total: Over 7.5 @ -110 via BetMGM (54% probability)

Dimers' best bets are based on complex simulations and betting intelligence to serve you the best possible plays every time.

While the Marlins are more likely to win the game, according to DimersBOT, betting on the Cardinals moneyline is the best option due to the edge found when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges seen here at Dimers is crucial to being a profitable sports bettor in the long run.

Cardinals vs. Marlins Betting Guide

Use our dynamic widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for St Louis vs. Miami, and click or tap on See Matchup for more.

Dimers has full betting coverage of Wednesday's Cardinals-Marlins matchup, including pre-game predictions, free picks, and live win probabilities.

Remember, DimersBOT updates frequently, so keep checking this article for any changes to our betting analysis before Cardinals vs. Marlins on Wednesday April 20, 2022.

Claim Your Risk-Free Bet for Cardinals vs. Marlins

Do you want a top online sportsbook offer for St Louis vs. Miami? Join Betway today and get a risk-free bet up to $1,000 in NJ and PA, and up to $250 in CO, IN and IA, which you can use on Wednesday's Cardinals-Marlins game.

Simply click or tap on this exclusive Betway link and create a new account – it's easy and takes no time at all.

Then, deposit funds and place a bet up to $1,000 in NJ and PA, and up to $250 in CO, IN and IA on Cardinals vs. Marlins. If you don't win your bet, Betway will give it back to you in site credit!

This promo is available to all new Betway users. How good is that!

Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Cardinals vs. Marlins 2022 Game Info

When do the Marlins play the Cardinals?

• Date: Wednesday April 20, 2022
• Time: 6:40PM EDT / 3:40PM PDT
• Venue: loanDepot park

Want to join an online sportsbook and start betting on MLB? We've listed the best available welcome offers for each and every legal betting state.

What MLB games are on today?

Now you've got the 411 on Cardinals vs. Marlins, see the latest betting analysis for all upcoming MLB games in our MLB Bet Hub, where you can find probabilities and odds, as well as our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

While you're here, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.