Cardinals vs. Giants Prediction and Odds - May 7, 2022

The San Francisco Giants take on the St Louis Cardinals in MLB action at Oracle Park on Saturday, beginning at 7:15PM ET.

The Giants will have Logan Webb (3-1, 3.26 ERA) start, up against Steven Matz (3-1, 4.56 ERA) for the Cardinals.

Dimers' free betting picks for Cardinals vs. Giants, as well as game predictions and best odds, are featured in this article.

Today's St Louis vs. San Francisco betting analysis is brought to you by PointsBet, which has an outstanding 5x $100 Risk-Free Bets offer for new customers.

Who will win Cardinals vs. Giants?

Using trusted computer power and data, Dimers.com has simulated Saturday's Cardinals-Giants MLB matchup 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, currently gives the Giants a 56% chance of beating the Cardinals.

More: Cardinals vs. Giants Simulated 10,000 Times

Cardinals vs. Giants Game Odds

• Run Line: Giants -1.5 (+155), Cardinals +1.5 (-175)
• Moneyline: Giants -150, Cardinals +135
• Total: Over/Under 6.5 (-110/+100)

Run Line, Moneyline and Over/Under

The Giants are listed as -1.5 favorites versus the Cardinals, with +155 at DraftKings Sportsbook the best odds currently available.

For the underdog Cardinals (+1.5) to cover the run line, Caesars Sportsbook has the best odds currently on the market at -175.

BetMGM currently has the best moneyline odds for the Giants at -150. That means you can risk $150 to win $100, for a total payout of $250, if they get the W.

Elsewhere, Caesars Sportsbook currently has the best moneyline odds for the Cardinals at +135, where you can bet $100 to profit $135, earning a total payout of $235, if they win.

The Over/Under is set at 6.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -110, while FanDuel Sportsbook currently has the best odds for the Under at +100.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Cardinals (+1.5) are a 65% chance of covering the run line, while the Over/Under total of 6.5 runs is a 56% chance of going Over.

More: Best Bets for Every MLB Matchup

Best Bets for Cardinals vs. Giants

• Run Line: Cardinals +1.5 @ -175 via Caesars Sportsbook (65% probability)
• Moneyline: Cardinals @ +135 via Caesars Sportsbook (1.5% edge)
• Total: Over 6.5 @ -110 via DraftKings Sportsbook (56% probability)

Dimers' best bets are based on detailed simulations and betting intelligence to bring you the best possible plays every time.

While the Giants are more likely to win the game, according to DimersBOT, betting on the Cardinals moneyline is the best option due to the 1.5% edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen on Dimers is crucial to achieving long-term profitability as a bettor.

Cardinals vs. Giants Betting Guide

Use our interactive widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for St Louis vs. San Francisco, and click or tap on See Matchup for more.

Dimers has full betting coverage of Saturday's Cardinals-Giants matchup, including pregame predictions, computer picks, and live win probabilities.

Remember, DimersBOT updates often, so keep an eye on this page for any changes to our betting analysis ahead of Cardinals vs. Giants on Saturday May 7, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Cardinals vs. Giants 2022 Game Info

When do the Giants play the Cardinals?

• Date: Saturday May 7, 2022
• Time: 7:15PM ET / 4:15PM PT
• Venue: Oracle Park

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What MLB games are on today?

Now you've got the 411 on Cardinals vs. Giants, check out the latest betting predictions for all upcoming MLB games in our MLB Bet Hub. There you can find probabilities and odds, as well as our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

While you're here, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds on the market.