Cardinals vs. Brewers Prediction and Odds - Jun 22, 2022

The Milwaukee Brewers and St Louis Cardinals are scheduled to meet in MLB at American Family Field on Wednesday, starting at 8:10PM ET.

Eric Lauer (6-2, 3.57 ERA) will start on the mound for the Brewers, while the Cardinals are going with Adam Wainwright (5-5, 3.06 ERA).

Dimers' top betting picks for Cardinals vs. Brewers, as well as game predictions and best odds, are detailed below.

Who will win Cardinals vs. Brewers?

Based on state-of-the-art machine learning and data, Dimers.com has simulated Wednesday's Cardinals-Brewers MLB game 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, currently gives the Cardinals a 51% chance of defeating the Brewers.

More: Cardinals vs. Brewers Simulated 10K Times

Cardinals vs. Brewers Game Odds

• Run Line: Brewers +1.5 (-184), Cardinals -1.5 (+160)
• Moneyline: Brewers -115, Cardinals +100
• Total: Over/Under 9 (+100/-112)

Run Line, Moneyline and Over/Under

The Brewers are +1.5 underdogs against the Cardinals, with -184 at FanDuel Sportsbook the best odds currently available.

For the favored Cardinals (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +160.

Caesars Sportsbook currently has the best moneyline odds for the Brewers at -115, which means you can risk $115 to win $100, for a total payout of $215, if they get the W.

Meanwhile, BetMGM currently has the best moneyline odds for the Cardinals at +100, where you can risk $100 to win $100, for a total payout of $200, if they come out on top.

The Over/Under is set at 9 with BetMGM, which currently has the best odds for the Over at +100, while FanDuel Sportsbook currently has the best odds for the Under at -112.

As always, check out all the sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Brewers (+1.5) are a 61% chance of covering the run line, while the Over/Under total of 9 runs is a 51% chance of going Under.

More: Free Online Bet Tracker

Best Bets for Cardinals vs. Brewers

• Run Line: Cardinals -1.5 @ +160 via DraftKings Sportsbook (0.4% edge)
• Moneyline: Cardinals @ +100 via BetMGM (51% probability)
• Total: Over 9 @ +100 via BetMGM

Our best bets are based on world-class modeling and wagering expertise to help you make smarter investments with the legal sportsbooks in your state.

Even though the Brewers are more likely to cover the run line, our best bet of Cardinals -1.5 is based on the chance of that happening, according to DimersBOT, and the top odds available.

Furthermore, despite the Under being more likely to hit on this occasion, Over 9 is our best bet owing to the better odds (+100) that are available from BetMGM.

Cardinals vs. Brewers Prediction

Use our widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for St Louis vs. Milwaukee, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Wednesday's Cardinals-Brewers matchup, including pregame predictions, free betting picks, and live win probabilities.

Remember, DimersBOT updates regularly, so keep an eye on this article for the latest betting insights before Cardinals vs. Brewers on Wednesday June 22, 2022.

Best Sportsbook Promo for Cardinals vs. Brewers

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Simply click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.

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Note: When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Cardinals vs. Brewers 2022 Game Info

Wednesday's game between the Brewers and Cardinals at American Family Field is scheduled to begin at 8:10PM ET.

• Who: Milwaukee Brewers vs. St Louis Cardinals
• Date: Wednesday June 22, 2022
• Time: 8:10PM ET / 5:10PM PT
• Venue: American Family Field

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Want more MLB predictions like this?

To get more MLB betting predictions like you've just read for Cardinals vs. Brewers, all you've gotta do is visit our MLB Betting News page. It's that easy – they're all there!

We use the power of predictive analytics to find edges in the markets so we can produce the best MLB betting previews available. We do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the bookies today – it's only a click away.

While you're here, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.