Canisius vs. Duquesne prediction: Duquesne favored to win men's college basketball matchup [12/22/2025]

Duquesne and Canisius are scheduled to meet in men's college basketball action at UPMC Cooper Fieldhouse on Monday, starting at 7:00 PM ET.

Based on the latest simulation results, Dimers' proven college basketball model predicts Duquesne as the most likely winner of the Canisius vs. Duquesne game.

This article offers an expanded analysis of Monday's matchup, including an expanded look at the predicted score, best bets and picks.

Canisius vs. Duquesne prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the result of Monday's NCAA basketball matchup between Canisius and Duquesne 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives Duquesne a 97% chance of defeating Canisius. Our predicted final score has Duquesne winning 83-62.

According to our model, Duquesne (-20.5) has a 52% chance of covering the spread, while the over/under total of 142.5 points has an equal 50-50 chance of hitting.

Canisius vs. Duquesne odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Canisius vs. Duquesne picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: