Cal Poly vs. UCLA prediction: UCLA favored to win men's college basketball matchup [12/19/2025]

Men's college basketball action continues on Friday at 10:00 PM ET as Cal Poly squares off with UCLA in men's college basketball action at Pauley Pavilion.

Based on updated simulations, Dimers' advanced college basketball model predicts UCLA as the most likely winner of the Cal Poly vs. UCLA game.

This article offers further insights into Friday's matchup, including an expanded look at the predicted score, best bets and picks.

Cal Poly vs. UCLA prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the result of Friday's NCAA basketball game between Cal Poly and UCLA 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model gives UCLA a 97% chance of beating Cal Poly. Our predicted final score has UCLA winning 89-65.

According to our model, the bookies have got it right, and Cal Poly and UCLA each have a 50% chance of covering the spread, while the over/under total of 160.5 points has a 55% chance of staying under.

Cal Poly vs. UCLA odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Cal Poly vs. UCLA picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: