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Butler vs. Creighton prediction: Why Creighton is favored to win men's college basketball matchup [12/30/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Butler vs Creighton predictions for college basketball Tuesday.
Creighton will face Butler in men's college basketball action at CHI Health Center Omaha on Tuesday, beginning at 9:00 PM ET.
Based on the latest simulation results, Dimers' advanced college basketball model predicts Creighton as the most likely winner of the Butler vs. Creighton game.
This article offers an expanded analysis of Tuesday's matchup, including an expanded look at the predicted score, best bets and picks.
Butler vs. Creighton prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the result of Tuesday's NCAA basketball matchup between Butler and Creighton 10,000 times as part of our men's college basketball predictions coverage.
Our independent predictive model gives Creighton a 72% chance of beating Butler. Our predicted final score has Creighton winning 81-74.
According to our model, Creighton (-5.5) has a 51% chance of covering the spread, while the over/under total of 156.5 points has an equal 50-50 chance of hitting.
Butler vs. Creighton odds
We have sourced the best men's college basketball odds in America for this game, which are listed here:
| Bet Type | Butler | Creighton |
|---|---|---|
| Spread | +5.5 (-102) | -5.5 (-118) |
| Moneyline | +215 | -250 |
| Total | o156.5 (-110) | u156.5 (-108) |
All odds are correct at the time of publication and are subject to change.
Butler vs. Creighton picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Butler +5.5 | -102 |
| Moneyline | Creighton | -250 |
| Total | Under 156.5 | -108 |
According to our men's college basketball best bets, the top play to make on this game is Creighton to win.
Butler vs. Creighton game-day updates and essential details
Tuesday's men's college basketball action between Creighton and Butler at CHI Health Center Omaha is scheduled to start at 9:00 PM ET.
- Who: Butler vs. Creighton
- Date: Tuesday, December 30, 2025
- Time: 9:00 PM ET/6:00PM PT
- Venue: CHI Health Center Omaha
Conclusion
We predict Creighton, with a 72% win probability, will likely beat Butler on Tuesday.
AI and automation have enhanced this article to quickly deliver accurate Butler vs. Creighton insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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