Buffalo vs. Western Michigan prediction: Why Buffalo is favored to win men's college basketball matchup [12/20/2025]

Western Michigan and Buffalo are scheduled to meet in men's college basketball action at University Arena on Saturday, with tipoff at 1:00 PM ET.

Based on updated simulations, Dimers' proven college basketball model predicts Buffalo as the most likely winner of the Buffalo vs. Western Michigan game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Buffalo vs. Western Michigan prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Saturday's NCAA basketball game between Buffalo and Western Michigan 10,000 times as part of our men's college basketball predictions coverage.

Our leading predictive model currently gives Buffalo a 55% chance of beating Western Michigan. Our predicted final score has Buffalo winning 75-74.

According to our model, Western Michigan (+1.5) has a 51% chance of covering the spread, while the over/under total of 150.5 points has a 54% chance of staying under.

Buffalo vs. Western Michigan odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Buffalo vs. Western Michigan picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: