Buffalo vs. East Carolina prediction: Why East Carolina is favored to win men's college basketball matchup [12/14/2025]

Men's college basketball action continues on Sunday at 1:00PM ET as Buffalo takes on East Carolina in men's college basketball action at Williams Arena at Minges Coliseum.

Based on updated simulation results, Dimers' proven college basketball model gives East Carolina a slight edge with a 53% win probability over Buffalo.

This article offers further insights into Sunday's Buffalo vs. East Carolina matchup, including an expanded look at the predicted score, best bets and picks.

Buffalo vs. East Carolina prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the result of Sunday's NCAA basketball matchup between Buffalo and East Carolina 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives East Carolina a 53% chance of beating Buffalo. Our predicted final score has East Carolina winning 73-72.

According to our model, Buffalo (+1.5) has a 55% chance of covering the spread, while the 146.5-point over/under has a 52% chance of staying under.

Buffalo vs. East Carolina odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Buffalo vs. East Carolina picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: