Bryant vs. Iona prediction: Why Iona is favored to win men's college basketball matchup [12/10/2025]

Iona and Bryant will lock horns in men's college basketball action at Hynes Athletics Center on Wednesday, with tipoff at 7:00PM ET.

Based on updated simulation results, Dimers' advanced college basketball model predicts Iona as the most likely winner of the Bryant vs. Iona game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Bryant vs. Iona prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball matchup between Bryant and Iona 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model currently gives Iona a 79% chance of defeating Bryant University. Our predicted final score has Iona winning 79-70.

According to our model, Bryant University (+9.5) has a 53% chance of covering the spread, while the 148.5-point over/under has a 52% chance of going over.

Bryant vs. Iona odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Bryant vs. Iona picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: