Brewers vs. Pirates Prediction and Odds - Apr 27, 2022

The Pittsburgh Pirates take on the Milwaukee Brewers in MLB action at PNC Park on Wednesday, starting at 6:35PM ET.

The Pirates will have Dillon Peters (3-0, 0.00 ERA) start, while the Brewers are going with Aaron Ashby (0-2, 3.18 ERA).

Dimers' best betting picks for Brewers vs. Pirates, plus game predictions and best odds, are detailed in this article.

Who will win Brewers vs. Pirates?

Based on state-of-the-art computer power and data, Dimers.com has simulated Wednesday's Brewers-Pirates MLB game 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, gives the Brewers a 60% chance of beating the Pirates.

More: Full Betting Guide for Brewers vs. Pirates

Brewers vs. Pirates Odds

• Run Line: Pirates +1.5 (-120), Brewers -1.5 (+100)
• Moneyline: Pirates +155, Brewers -170
• Total: Over/Under 7.5 (+105/-115)

Run Line, Moneyline and Over/Under

The Pirates are +1.5 underdogs versus the Brewers, with -120 at DraftKings Sportsbook the best odds currently available.

For the favored Brewers (-1.5) to cover the run line, BetMGM has the best odds currently on the market at +100.

Caesars Sportsbook currently has the best moneyline odds for the Pirates at +155, which means you can throw down $100 to profit $155, earning a total payout of $255, if they win.

On the other hand, DraftKings Sportsbook currently has the best moneyline odds for the Brewers at -170, where you can risk $170 to win $100, for a total payout of $270, if they come out on top.

The Over/Under sits at 7.5 with PointsBet, which currently has the best odds for the Over at +105, while Caesars Sportsbook currently has the best odds for the Under at -115.

As always, make sure you check the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Pirates (+1.5) are a 55% chance of covering the run line, while the 7.5-run Over/Under is considered an equal 50-50 chance of hitting.

More: Today's Best Bets for All Major Sports

Best Bets for Brewers vs. Pirates

• Run Line: Pirates +1.5 @ -120 via DraftKings Sportsbook (55% probability)
• Moneyline: Pirates @ +155 via Caesars Sportsbook (1.3% edge)
• Total: Over 7.5 @ +105 via PointsBet (50% probability)

Dimers' best bets are based on complex simulations and wagering intelligence to serve you the best possible plays every time.

While the Brewers are more likely to win the game, according to DimersBOT, taking the Pirates moneyline is the best option because of the 1.3% edge found when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges seen here at Dimers.com is crucial to achieving long-term profitability as a sports bettor.

Brewers vs. Pirates Probabilities

Use our dynamic widget below to see up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Milwaukee vs. Pittsburgh, and click or tap on See Matchup for more.

Dimers has full coverage of Wednesday's Brewers-Pirates matchup, including pregame predictions, computer picks, and live scores.

Don't forget, DimersBOT updates regularly, so refresh this article for any changes to our betting insights before Brewers vs. Pirates on Wednesday April 27, 2022.

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Brewers vs. Pirates 2022 Game Info

When do the Pirates play the Brewers?

• Date: Wednesday April 27, 2022
• Time: 6:35PM ET / 3:35PM PT
• Venue: PNC Park

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What MLB games are on today?

Now you've got the 411 on Brewers vs. Pirates, see the latest betting coverage for all upcoming MLB games in Dimers' MLB Bet Hub, where you can find probabilities and odds, plus our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

While you're here, Dimers' MLB Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.