Brewers vs. Cubs Prediction and Odds - Apr 7, 2022

The Chicago Cubs take on the Milwaukee Brewers on Opening Day of the 2022 MLB season at Wrigley Field on Thursday, starting at 2:20PM EDT.

Kyle Hendricks (0-0, 0.00 ERA) will get the ball for the Cubs, pitting him against Corbin Burnes (0-0, 0.00 ERA) for the Brewers.

Dimers' best betting picks for Brewers vs. Cubs, as well as game predictions and best odds, are detailed in this article.

Who will win Brewers vs. Cubs?

Based on cutting-edge machine learning and data, Dimers.com has simulated Thursday's Brewers-Cubs MLB game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives the Brewers a 60% chance of beating the Cubs.

MORE: Brewers vs. Cubs Simulated 10K Times

Run Line, Moneyline and Over/Under

The Cubs are listed as +1.5 underdogs against the Brewers, with +100 at Caesars Sportsbook the best odds currently available.

For the favored Brewers (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at -110.

Caesars Sportsbook currently has the best moneyline odds for the Cubs at +165. That means you can bet $100 to profit $165, earning a total payout of $265, if they win.

On the other hand, DraftKings Sportsbook currently has the best moneyline odds for the Brewers at -180, where you can risk $180 to win $100, for a total payout of $280, if they come out on top.

The Over/Under for total runs scored sits at 10 with DraftKings Sportsbook, which currently has the best odds for the Over at -115, as well as the best odds for the Under at -105.

As always, make sure you check all the sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Cubs (+1.5) are a 53% chance of covering the run line, while the 10-run Over/Under is a 61% chance of going Under.

MORE: Predictions for Every MLB Matchup

Best Bets for Brewers vs. Cubs

• Run Line: Cubs +1.5 @ +100 via Caesars Sportsbook (53% probability)
• Moneyline: Cubs @ +165 via Caesars Sportsbook (2.5% edge)
• Over/Under: Under 10 @ -105 via DraftKings Sportsbook (61% probability) 🔥

When you see a 🔥, you know it's one of Dimers' best bets of the day across any sport.

Dimers' best bets are based on detailed simulations and betting intelligence to bring you the best possible plays every time.

While the Brewers are more likely to win the game, according to DimersBOT, betting on the Cubs moneyline is the best option because of the 2.5% edge found when comparing our data-led probabilities to the sportsbooks' odds currently available.

Taking advantage of the edges seen on Dimers.com is crucial to achieving long-term profitability.

Brewers vs. Cubs Probabilities

Use our dynamic widget below to see up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Milwaukee vs. CHI Cubs, and click or tap on See Matchup for more.

Dimers has full coverage of Thursday's Brewers-Cubs matchup, including pre-game predictions, top betting picks, and live win probabilities.

Remember, DimersBOT updates often, so keep an eye on this page for the latest betting insights before Brewers vs. Cubs on Thursday April 7, 2022.

Best Betting Promo for Brewers vs. Cubs

Do you want the best sportsbook promo in America for Milwaukee vs. CHI Cubs? Join FanDuel Sportsbook today and get a risk-free first bet up to $1,000, which you can use on Thursday's Brewers-Cubs matchup.

All you need to do is click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.

Then, make your first deposit and place a bet up to $1K on Brewers vs. Cubs. If your bet doesn't win, FanDuel Sportsbook will give it back to you in site credit!

This offer is available to all new FanDuel Sportsbook users. How good is that!

Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Brewers vs. Cubs 2022 Game Info

When do the Cubs play the Brewers?

• Date: Thursday April 7, 2022
• Time: 2:20PM EDT / 11:20AM PDT
• Venue: Wrigley Field

Enjoy Dimers and want to keep the site free? Every time you join a sportsbook featured here, we get paid a small fee.

These fees help us keep Dimers free for sports fans like you. So, if you like what you see, support us by joining one of our featured sports betting partners.

What MLB games are on today?

Now you've got the 411 on Brewers vs. Cubs, get the latest betting analysis for all upcoming MLB games in Dimers' MLB Bet Hub. There you can find probabilities and odds, plus our best bets for every single MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!