Blue Jays vs. White Sox Prediction and Odds - Jun 22, 2022

The Chicago White Sox and Toronto Blue Jays are scheduled to meet in MLB at Guaranteed Rate Field on Wednesday, starting at 2:10PM ET.

The White Sox will send Lucas Giolito (4-3, 4.78 ERA) to the mound, up against Ross Stripling (3-2, 3.28 ERA) for the Blue Jays.

Dimers' best betting picks for Blue Jays vs. White Sox, plus game predictions and best odds, are featured below.

Who will win Blue Jays vs. White Sox?

Based on cutting-edge machine learning and data, Dimers.com has simulated Wednesday's Blue Jays-White Sox MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Blue Jays a 51% chance of winning against the White Sox.

More: Free Betting Analysis for Blue Jays vs. White Sox

Blue Jays vs. White Sox Odds

• Run Line: White Sox +1.5 (-155), Blue Jays -1.5 (+140)
• Moneyline: White Sox +100, Blue Jays -110
• Total: Over/Under 9 (-102/-110)

Run Line, Moneyline and Over/Under

The White Sox are +1.5 underdogs versus the Blue Jays, with -155 at PointsBet the best odds currently available.

For the favored Blue Jays (-1.5) to cover the run line, Caesars Sportsbook has the best odds currently on offer at +140.

BetMGM currently has the best moneyline odds for the White Sox at +100. That means you can risk $100 to win $100, for a total payout of $200, if they get the W.

Meanwhile, Caesars Sportsbook currently has the best moneyline odds for the Blue Jays at -110, where you can risk $110 to win $100, for a total payout of $210, if they come out on top.

The Over/Under for total runs scored is set at 9 with FanDuel Sportsbook, which currently has the best odds for the Over at -102, while Caesars Sportsbook currently has the best odds for the Under at -110.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the White Sox (+1.5) are a 62% chance of covering the run line, while the 9-run Over/Under is a 54% chance of going Over.

More: Best Bets Today for All Major Sports

Best Bets for Blue Jays vs. White Sox

• Run Line: White Sox +1.5 @ -155 via PointsBet (62% probability)
• Moneyline: White Sox @ +100 via BetMGM
• Total: Over 9 @ -102 via FanDuel Sportsbook (54% probability)

Our best bets are based on detailed modeling and betting expertise to help you make better investments with your state's legal sportsbooks.

While the Blue Jays are more likely to win the game, according to DimersBOT, taking the White Sox moneyline is the best option because of the edge found when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published on Dimers is pivotal to achieving long-term profitability.

Blue Jays vs. White Sox Prediction

Use our interactive widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Toronto vs. CHI White Sox, and click or tap on See Matchup for more.

Dimers has full coverage of Wednesday's Blue Jays-White Sox matchup, including pregame predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep an eye on this article for any changes to our betting insights before Blue Jays vs. White Sox on Wednesday June 22, 2022.

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Note: When you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may receive a referral fee.

Blue Jays vs. White Sox 2022 Game Info

Wednesday's matchup between the White Sox and Blue Jays at Guaranteed Rate Field is scheduled to begin at 2:10PM ET.

• Who: Chicago White Sox vs. Toronto Blue Jays
• Date: Wednesday June 22, 2022
• Time: 2:10PM ET / 11:10AM PT
• Venue: Guaranteed Rate Field

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Want more MLB previews like this?

So, you liked our Blue Jays vs. White Sox betting predictions? Awesome. Did you know our MLB Betting News section has a detailed betting preview for every MLB matchup as soon as the sportsbooks release their odds?

That's right, our predictive analytics model then compares those odds against its own probabilities to find edges in the markets, which allows us to create the most accurate MLB betting previews and get the jump on the public and the sportsbooks.

It's only a click away, so why not take a look around?

While you're here, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.