Blue Jays vs. White Sox Prediction and Odds - Jun 21, 2022

The Chicago White Sox and Toronto Blue Jays clash in MLB at Guaranteed Rate Field on Tuesday, starting at 8:10PM ET.

Dylan Cease (5-3, 2.91 ERA) will start on the mound for the White Sox, while the Blue Jays will counter with Kevin Gausman (5-6, 3.20 ERA).

Dimers' best betting picks for Blue Jays vs. White Sox, as well as game predictions and best odds, are detailed in this article.

Who will win Blue Jays vs. White Sox?

Using state-of-the-art machine learning and data, Dimers.com has simulated Tuesday's Blue Jays-White Sox MLB game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives the Blue Jays a 52% chance of getting the W against the White Sox.

More: Free Betting Analysis for Blue Jays vs. White Sox

Blue Jays vs. White Sox Odds

• Run Line: White Sox +1.5 (-138), Blue Jays -1.5 (+130)
• Moneyline: White Sox +115, Blue Jays -130
• Total: Over/Under 9 (-110/-105)

Run Line, Moneyline and Over/Under

The White Sox are +1.5 underdogs against the Blue Jays, with -138 at FanDuel Sportsbook the best odds currently available.

For the favored Blue Jays (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +130.

BetMGM currently has the best moneyline odds for the White Sox at +115. That means you can bet $100 to profit $115, earning a total payout of $215, if they win.

Meanwhile, Caesars Sportsbook currently has the best moneyline odds for the Blue Jays at -130, where you can risk $130 to win $100, for a total payout of $230, if they come out on top.

The Over/Under for total runs scored is set at 9 with BetMGM, which currently has the best odds for the Over at -110, while PointsBet currently has the best odds for the Under at -105.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the White Sox (+1.5) are a 59% chance of covering the run line, while the Over/Under total of 9 runs is a 53% chance of going Over.

More: Free Online Bet Tracking Tool

Best Bets for Blue Jays vs. White Sox

• Run Line: White Sox +1.5 @ -138 via FanDuel Sportsbook (59% probability)
• Moneyline: White Sox @ +115 via BetMGM (1.7% edge)
• Total: Over 9 @ -110 via BetMGM (53% probability)

Dimers' best bets are based on world-class simulations and betting expertise to help you make more informed investments with your state's legal sportsbooks.

While the Blue Jays are more likely to win the game, according to DimersBOT, taking the White Sox moneyline is the best option because of the 1.7% edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen here at Dimers.com is crucial to being a profitable sports bettor in the long run.

Blue Jays vs. White Sox Prediction

Use our interactive widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for Toronto vs. CHI White Sox, and click or tap on See Matchup for more.

Dimers has full betting coverage of Tuesday's Blue Jays-White Sox matchup, including pregame predictions, free betting picks, and live updates.

Don't forget, DimersBOT updates often, so keep an eye on this page for the latest betting analysis ahead of Blue Jays vs. White Sox on Tuesday June 21, 2022.

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Blue Jays vs. White Sox 2022 Game Info

Tuesday's matchup between the White Sox and Blue Jays at Guaranteed Rate Field is scheduled to begin at 8:10PM ET.

• Who: Chicago White Sox vs. Toronto Blue Jays
• Date: Tuesday June 21, 2022
• Time: 8:10PM ET / 5:10PM PT
• Venue: Guaranteed Rate Field

Want to join an online sportsbook and start betting on MLB now? Check out the top sports betting offers in your state.

What other MLB games are on today?

Now you've got the 411 on Blue Jays vs. White Sox, get the latest betting predictions for all upcoming MLB games in Dimers' MLB Bet Hub. There you can find probabilities and odds, plus our best bets for each and every MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Finally, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.