Blue Jays vs. Red Sox Prediction and Odds - Apr 21, 2022

MLB action continues on Thursday at 1:35PM ET as the Toronto Blue Jays lock horns with the Boston Red Sox at Fenway Park.

Tanner Houck (1-0, 3.00 ERA) will get the ball for the Red Sox, pitting him against Kevin Gausman (0-1, 4.22 ERA) for the Blue Jays.

Dimers' best betting picks for Blue Jays vs. Red Sox, as well as game predictions and best odds, are detailed below.

Who will win Blue Jays vs. Red Sox?

Using advanced computer power and data, Dimers.com has simulated Thursday's Blue Jays-Red Sox MLB matchup 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently gives the Red Sox a 53% chance of defeating the Blue Jays.

More: Free Betting Analysis for Blue Jays vs. Red Sox

Blue Jays vs. Red Sox Current Odds

• Run Line: Red Sox +1.5 (-156), Blue Jays -1.5 (+145)
• Moneyline: Red Sox -102, Blue Jays -115
• Total: Over/Under 8.5 (-110/+105)

Run Line, Moneyline and Over/Under

The Red Sox are +1.5 underdogs against the Blue Jays, with -156 at FanDuel Sportsbook the best odds currently available.

For the favored Blue Jays (-1.5) to cover the run line, PointsBet has the best odds currently on offer at +145.

In a sign of how close this game is expected to be, both the Red Sox and Blue Jays are currently at minus-money betting odds on the moneyline.

FanDuel Sportsbook currently has the best moneyline odds for the Red Sox at -102. That means you can risk $102 to win $100, for a total payout of $202, if they get the W.

Elsewhere, Caesars Sportsbook currently has the best moneyline odds for the Blue Jays at -115, where you can risk $115 to win $100, for a total payout of $215, if they come out on top.

The Over/Under for total runs scored is set at 8.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -110, while Caesars Sportsbook currently has the best odds for the Under at +105.

As always, check out all the sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Red Sox (+1.5) are a 65% chance of covering the run line, while the Over/Under total of 8.5 runs is a 53% chance of going Over.

More: Best Bets Today for All Major Sports

Best Bets for Blue Jays vs. Red Sox

• Run Line: Red Sox +1.5 @ -156 via FanDuel Sportsbook (65% probability) 🔥
• Moneyline: Red Sox @ -102 via FanDuel Sportsbook (53% probability)
• Total: Over 8.5 @ -110 via FanDuel Sportsbook (53% probability)

Any time you see a 🔥, you know it's one of our best free picks today across all major pro and college sports.

Dimers' best bets are based on complex simulations and betting intelligence to bring you the best possible plays 24/7.

Blue Jays vs. Red Sox Probabilities

Use our widget below to see up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Toronto vs. Boston, and click or tap on See Matchup for more.

Dimers has full betting coverage of Thursday's Blue Jays-Red Sox matchup, including pregame predictions, free picks, and live win probabilities.

Don't forget, DimersBOT updates often, so refresh this page for the latest betting insights before Blue Jays vs. Red Sox on Thursday April 21, 2022.

Best Sportsbook Promo for Blue Jays vs. Red Sox

Looking for the best sportsbook offer in America for Toronto vs. Boston? Join FanDuel Sportsbook now and get your first bet risk free up to $1,000, which you can use on Thursday's Blue Jays-Red Sox matchup.

Simply click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.

Then, make your first deposit and place a bet up to $1,000 on Blue Jays vs. Red Sox. If you don't win your bet, FanDuel Sportsbook will give it back to you in site credit!

This offer is available to all new FanDuel Sportsbook users. How good is that!

Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Blue Jays vs. Red Sox 2022 Game Info

When do the Red Sox play the Blue Jays?

• Date: Thursday April 21, 2022
• Time: 1:35PM ET / 10:35AM PT
• Venue: Fenway Park

Want to join an online sportsbook and start betting on MLB? Check out the best sportsbook offers in your state.

Want more MLB previews like this?

To get more MLB betting previews like you've just read for Blue Jays vs. Red Sox, all you've gotta do is visit our MLB Betting News section. It's that easy – they're all there!

We use the power of predictive analytics to find value in the markets so we can produce the most comprehensive MLB betting previews out there. We do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.

Lastly, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds on the market.