Blue Jays vs. Guardians Prediction and Odds - May 7, 2022

The Cleveland Guardians and Toronto Blue Jays clash in MLB at Progressive Field on Saturday, starting at 6:10PM ET.

Triston McKenzie (1-2, 2.70 ERA) will get the ball for the Guardians, up against Ross Stripling (0-0, 3.79 ERA) for the Blue Jays.

Dimers' top betting picks for Blue Jays vs. Guardians, plus game predictions and best odds, are detailed in this article.

This Toronto vs. Cleveland betting analysis is brought to you by PointsBet, which has an outstanding 5x $100 Risk-Free Bets offer for new customers.

Who will win Blue Jays vs. Guardians?

Based on trusted machine learning and data, Dimers.com has simulated Saturday's Blue Jays-Guardians MLB game 10,000 times.

Dimers' famous predictive analytics model, DimersBOT, gives the Blue Jays a 53% chance of defeating the Guardians.

More: Blue Jays vs. Guardians Simulated 10K Times

Blue Jays vs. Guardians Current Odds

• Run Line: Guardians +1.5 (-149), Blue Jays -1.5 (+132)
• Moneyline: Guardians +116, Blue Jays -130
• Total: Over/Under 7.5 (-110/-105)

Run Line, Moneyline and Over/Under

The Guardians are +1.5 underdogs against the Blue Jays, with -149 at Caesars Sportsbook the best odds currently available.

For the favored Blue Jays (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +132.

FanDuel Sportsbook currently has the best moneyline odds for the Guardians at +116. That means you can bet $100 to profit $116, earning a total payout of $216, if they win.

Elsewhere, DraftKings Sportsbook currently has the best moneyline odds for the Blue Jays at -130, where you can risk $130 to win $100, for a total payout of $230, if they come out on top.

The Over/Under sits at 7.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -110, while BetMGM currently has the best odds for the Under at -105.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Guardians (+1.5) are a 62% chance of covering the run line, while the 7.5-run Over/Under is considered an equal 50-50 chance of hitting.

More: Today's Best Bets for All Major Sports

Best Bets for Blue Jays vs. Guardians

• Run Line: Guardians +1.5 @ -149 via Caesars Sportsbook (62% probability)
• Moneyline: Guardians @ +116 via FanDuel Sportsbook (0.7% edge)
• Total: Under 7.5 @ -105 via BetMGM (50% probability)

Dimers' best bets are based on detailed simulations and betting intelligence to bring you the best possible plays 24/7/365.

While the Blue Jays are more likely to win the game, according to DimersBOT, betting on the Guardians moneyline is the best option because of the edge identified when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges seen on Dimers.com is pivotal to achieving long-term profitability.

Blue Jays vs. Guardians Betting Guide

Use our interactive widget below to see up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Toronto vs. Cleveland, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Saturday's Blue Jays-Guardians matchup, including pregame predictions, computer picks, and live win probabilities.

Remember, DimersBOT updates regularly, so keep checking this article for the latest betting analysis ahead of Blue Jays vs. Guardians on Saturday May 7, 2022.

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Blue Jays vs. Guardians 2022 Game Info

When do the Guardians play the Blue Jays?

• Date: Saturday May 7, 2022
• Time: 6:10PM ET / 3:10PM PT
• Venue: Progressive Field

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