Blue Jays vs. Astros Prediction and Odds - Apr 23, 2022

The Houston Astros and Toronto Blue Jays are scheduled to meet in MLB at Minute Maid Park on Saturday, starting at 4:10PM ET.

The Astros will send José Urquidy (1-1, 7.00 ERA) to the mound, while the Blue Jays will counter with Alek Manoah (2-0, 1.50 ERA).

Dimers' top betting picks for Blue Jays vs. Astros, as well as game predictions and best odds, are featured below.

Who will win Blue Jays vs. Astros?

Using high-tech machine learning and data, Dimers.com has simulated Saturday's Blue Jays-Astros MLB matchup 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, currently gives the Astros a 53% chance of defeating the Blue Jays.

More: Full Betting Analysis for Blue Jays vs. Astros

Blue Jays vs. Astros Current Odds

• Run Line: Astros +1.5 (-145), Blue Jays -1.5 (+140)
• Moneyline: Astros +110, Blue Jays -120
• Total: Over/Under 8.5 (-110/-105)

Run Line, Moneyline and Over/Under

The Astros are +1.5 underdogs versus the Blue Jays, with -145 at PointsBet the best odds currently available.

For the favored Blue Jays (-1.5) to cover the run line, Caesars Sportsbook has the best odds currently on the market at +140.

BetMGM currently has the best moneyline odds for the Astros at +110, which means you can bet $100 to profit $110, earning a total payout of $210, if they win.

Elsewhere, Caesars Sportsbook currently has the best moneyline odds for the Blue Jays at -120, where you can risk $120 to win $100, for a total payout of $220, if they come out on top.

The Over/Under for total runs scored is set at 8.5 with Caesars Sportsbook, which currently has the best odds for the Over at -110, while DraftKings Sportsbook currently has the best odds for the Under at -105.

As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Blue Jays (-1.5) are a 51% chance of covering the run line, while the 8.5-run Over/Under is a 52% chance of going Over.

More: Live Win Probabilities for All Major Sports

Best Bets for Blue Jays vs. Astros

• Run Line: Blue Jays -1.5 @ +140 via Caesars Sportsbook (51% probability) 🔥
• Moneyline: Astros @ +110 via BetMGM (53% probability) 🔥
• Total: Over 8.5 @ -110 via Caesars Sportsbook (52% probability)

If you see a 🔥, you know you've found one of Dimers' best bets today across all sports.

Dimers' best bets are based on world-class simulations and betting intelligence to serve you the best possible plays every time.

Blue Jays vs. Astros Betting Guide

Use our interactive widget below to see up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Toronto vs. Houston, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Saturday's Blue Jays-Astros matchup, including pregame predictions, free picks, and live updates.

Remember, DimersBOT updates frequently, so keep checking this page for any changes to our betting insights ahead of Blue Jays vs. Astros on Saturday April 23, 2022.

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Blue Jays vs. Astros 2022 Game Info

When do the Astros play the Blue Jays?

• Date: Saturday April 23, 2022
• Time: 4:10PM ET / 1:10PM PT
• Venue: Minute Maid Park

Ready to join an online sportsbook and start betting on MLB? We've listed the best available sign-up offers for every legal betting state.

What MLB games are on today?

The Blue Jays and Astros aren't the only two MLB teams you can bet on today. DimersBOT never stops and we've got picks and top bets for each and every MLB matchup in our MLB Bet Hub page.

Not only do we provide with you top-notch predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Hell yeah it does!

Finally, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities paired with the best odds to win the World Series.