Blue Jackets vs. Sabres Predictions and Odds - Nov 22, 2021

The Buffalo Sabres and Columbus Blue Jackets clash in the NHL at KeyBank Center on Monday, starting at 7:00 PM EST.

Dimers' top betting picks for Blue Jackets vs. Sabres, plus game predictions and best odds, are detailed below.

Who will win Blue Jackets vs. Sabres?

Using advanced computer power and data, Dimers.com has simulated Monday's Blue Jackets-Sabres game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Blue Jackets a 52% chance of getting the W against the Sabres.

MORE: Blue Jackets vs. Sabres Simulated 10,000 Times

Blue Jackets vs. Sabres Puck Line, Moneyline and Over/Under

The Sabres are against the Blue Jackets, with at the best odds available.

For the Blue Jackets (-0) to cover the puck line, also has the best odds on offer at .

DraftKings Sportsbook has the best moneyline odds for the Sabres at +115. That means you can bet $100 to profit $115, earning a total payout of $215, if they win.

Meanwhile, FanDuel Sportsbook has the best moneyline odds for the Blue Jackets at -126, where you can risk $126 to win $100, for a total payout of $226, if they come out on top.

The Over/Under for total goals scored is set at 5.5 with FanDuel Sportsbook, which has the best odds for the Over at -118, while PointsBet has the best odds for the Under at +105.

As always, check out the sportsbooks you can bet with in your state for the best NHL odds and lines.

According to DimersBOT, the bookmakers have got it right and both the Blue Jackets and Sabres are a 50% chance of covering the puck line, while the Over/Under total of 5.5 goals is a 51% chance of going Over.

MORE: Predictions for Every NHL 2021 Matchup

Best Bets for Blue Jackets vs. Sabres

• Moneyline: Sabres Win at +115 with DraftKings Sportsbook (1.6% edge)
• Over/Under: Under 5.5 at +105 with PointsBet (0.4% edge)

While the Blue Jackets are more likely to win the game, according to DimersBOT, betting on the Sabres moneyline is the best option due to the 1.6% edge found when comparing our data-led probabilities to the sportsbooks' odds.

Taking advantage of the edges seen here at Dimers.com is one of the keys to being profitable in the long run.

Furthermore, despite the Over being more likely to hit on this occasion, Under 5.5 is our best bet on account of the better odds (+105) that are available from PointsBet.

Blue Jackets vs. Sabres Betting Insights

Use our interactive widget below to view the current Moneyline, Over/Under and Puck Line probabilities and odds for Columbus vs. Buffalo, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Monday's Blue Jackets-Sabres matchup, including pre-game predictions, computer picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep checking this page for the latest betting insights ahead of Blue Jackets vs. Sabres on Monday November 22, 2021.

Blue Jackets vs. Sabres 2021 Game Info

When do the Sabres play the Blue Jackets?

• Date: Monday November 22, 2021
• Time: 7:00 PM EST / 4:00 PM PST
• Venue: KeyBank Center

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