Baltimore Orioles vs. St. Louis Cardinals Prediction, Odds, MLB Picks [5/21/2024]

Baltimore Orioles vs. St. Louis Cardinals Prediction, Odds, MLB Picks [5/21/2024]

The St. Louis Cardinals will face the Baltimore Orioles in MLB action at Busch Stadium on Tuesday, starting at 7:45PM ET.

Lance Lynn (1-2, 4.17 ERA) will get the ball for the Cardinals, up against Kyle Bradish (0-0, 2.63 ERA) for the Orioles.'s full preview of Tuesday's Orioles vs. Cardinals matchup includes our prediction, picks and the latest betting odds.

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Orioles vs. Cardinals Prediction: Who Will Win, Cover the Run Line

We have used powerful machine learning and data to simulate the result of Tuesday's MLB matchup between the Orioles and Cardinals 10,000 times, in line with our coverage of MLB predictions.

Our independent predictive analytics model currently gives the Orioles a 56% chance of beating the Cardinals.

According to our model, the Cardinals (+1.5) have a 56% chance of covering the run line, while the over/under total of 9 runs has a 52% chance of going under.

Orioles vs. Cardinals Odds [5/21/2024]

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type Orioles Cardinals
Run Line -1.5 (-104) +1.5 (-112)
Moneyline -162 +140
Total o9 (-110) u9 (-108)

All odds are correct at the time of publication and are subject to change.

Orioles vs. Cardinals Picks

At Dimers, our predictions, coupled with the current odds, reveal the top betting picks to make on every game, including Orioles vs. Cardinals. Our MLB best bets are based on expert modeling and analysis, as you can see.

With a betting edge of 2.2%, a pick from the Orioles vs. Cardinals game is featured in today's best bets on Dimers Pro.

Through Dimers Pro, we give you the tools and information to succeed with hundreds of data-driven bets across thousands of games. Join now to find the pick we have for this game.


Orioles vs. Cardinals Game Information

Tuesday's MLB game between the Cardinals and Orioles at Busch Stadium is scheduled to start at 7:45PM ET.


Our full coverage of the Orioles vs. Cardinals includes pregame predictions, betting picks and live win probabilities.

Calling Our Shot: Best Bets Video

Calling Our Shot produces daily MLB betting content, including the free picks featured below.


We predict the Orioles, with a 56% win probability, will likely beat the Cardinals on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Orioles vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are based on current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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Dave Garofolo
Content Producer

Dave Garofolo, a seasoned fantasy sports and betting enthusiast with a special affection for MLB and NFL, uses his deep knowledge to craft game previews for the NBA, MLB, and NFL. He also brings his expertise to the golf world with tournament previews and parlays for the PGA TOUR and major golf tournaments. Additionally, Dave offers valuable props for NBA, MLB, NHL, and NCAAM basketball, along with best bets for MLB, NHL, and NCAAM. 

When not delving into the world of sports, Dave is an avid advocate for New Haven pizza, enjoys reading comic books, gardening, and spending time with his cats. His broad interests and detailed sports insights ensure that his contributions are both engaging and informative.

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