Orioles vs. Yankees prediction: Yankees favored to win Monday's MLB matchup [5/4/2026]
Get Baltimore Orioles vs New York Yankees predictions for MLB Monday.

MLB action continues on Monday at 7:05 PM ET as the Baltimore Orioles take on the favored New York Yankees at Yankee Stadium.
Cam Schlittler (4-1, 1.51 ERA) will start on the mound for the Yankees, pitting him against Shane Baz (1-2, 4.50 ERA) for the Orioles.
Based on the latest simulation results, Dimers' advanced MLB model projects the Yankees as the most likely winner of the Orioles vs. Yankees game.
This article offers further insights into Monday's matchup, including best bets and picks.
Orioles vs. Yankees prediction: Who will win and cover?
Our famous predictive model currently gives the Yankees a 64% chance of beating the Orioles.
According to our model, the Orioles (+1.5) have a 52% chance of covering the run line, while the 8.5-run over/under has a 55% chance of going over.
Orioles vs. Yankees odds [5/4/2026]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Orioles | Yankees |
|---|---|---|
| Run Line | +1.5 (-108) | -1.5 (-102) |
| Moneyline | +189 | -215 |
| Total | o8.5 (-105) | u8.5 (-112) |
All odds are correct at the time of publication and are subject to change.
Orioles vs. Yankees picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Orioles +1.5 | -108 |
| Moneyline | Orioles | +189 |
| Total | Over 8.5 | -105 |
According to our best MLB bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Orioles vs. Yankees game-day updates and essential details
Monday's MLB game between the Yankees and Orioles at Yankee Stadium is scheduled to commence at 7:05 PM ET.
- Who: Baltimore Orioles vs. New York Yankees
- Date: Monday, May 4, 2026
- Time: 7:05 PM ET/4:05PM PT
- Venue: Yankee Stadium
Conclusion
We predict the Yankees, with a 64% win probability, will likely beat the Orioles in Monday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.



