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Orioles vs. Yankees prediction: Yankees favored to win Monday's MLB matchup [5/4/2026]
Get Baltimore Orioles vs New York Yankees predictions for MLB Monday.

The New York Yankees and Baltimore Orioles will lock horns in MLB action at Yankee Stadium on Monday, starting at 7:05 PM ET.
The Yankees will start Cam Schlittler (4-1, 1.51 ERA), pitting him against Shane Baz (1-2, 4.50 ERA) for the Orioles.
Based on the latest simulations, Dimers' proven MLB model projects the Yankees as the most likely winner of the Orioles vs. Yankees game.
This article offers further insights into Monday's matchup, including best bets and picks.
Orioles vs. Yankees prediction: Who will win and cover?
Our leading predictive model currently gives the Yankees a 64% chance of defeating the Orioles.
According to our model, the Orioles (+1.5) have a 52% chance of covering the run line, while the over/under total of 8.5 runs has a 54% chance of going over.
Orioles vs. Yankees odds [5/4/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Orioles | Yankees |
|---|---|---|
| Run Line | +1.5 (-112) | -1.5 (-104) |
| Moneyline | +185 | -215 |
| Total | o8.5 (-105) | u8.5 (-112) |
All odds are correct at the time of publication and are subject to change.
Orioles vs. Yankees picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Orioles +1.5 | -112 |
| Moneyline | Orioles | +185 |
| Total | Over 8.5 | -105 |
According to our MLB best bets, the top play to make on this game is Over 8.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Orioles vs. Yankees game-day updates and essential details
Monday's MLB action between the Yankees and Orioles at Yankee Stadium is scheduled to start at 7:05 PM ET.
- Who: Baltimore Orioles vs. New York Yankees
- Date: Monday, May 4, 2026
- Time: 7:05 PM ET/4:05PM PT
- Venue: Yankee Stadium
Conclusion
We predict the Yankees, with a 64% win probability, will likely beat the Orioles in Monday's MLB matchup.
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