Astros vs. White Sox Prediction and Odds - Aug 17, 2022

The Chicago White Sox square off with the Houston Astros in MLB action at Guaranteed Rate Field on Wednesday, beginning at 8:10PM ET.

The White Sox will send Michael Kopech (4-8, 3.18 ERA) to the mound, while the Astros will counter with Framber Valdez (11-4, 2.72 ERA).

Dimers' best betting picks for Astros vs. White Sox, plus game predictions and best odds, are featured in this article.

Who will win Astros vs. White Sox?

Based on cutting-edge machine learning and data, Dimers.com has simulated Wednesday's Astros-White Sox MLB game 10,000 times.

Dimers' popular predictive analytics model, DimersBOT, gives the Astros a 54% chance of beating the White Sox.

More: Astros vs. White Sox Simulated 10,000 Times

Astros vs. White Sox Odds

• Run Line: White Sox +1.5 (-130), Astros -1.5 (+115)
• Moneyline: White Sox +130, Astros -145
• Total: Over/Under 8 (-105/-105)

Run Line, Moneyline and Over/Under

The White Sox are listed as +1.5 underdogs versus the Astros, with -130 at Caesars Sportsbook the best odds currently available.

For the favored Astros (-1.5) to cover the run line, BetMGM has the best odds currently on offer at +115.

DraftKings Sportsbook currently has the best moneyline odds for the White Sox at +130, which means you can bet $100 to profit $130, earning a total payout of $230, if they win.

On the other hand, BetMGM currently has the best moneyline odds for the Astros at -145, where you can risk $145 to win $100, for a total payout of $245, if they come out on top.

The Over/Under for total runs scored sits at 8 with PointsBet, which currently has the best odds for the Over at -105, while DraftKings Sportsbook currently has the best odds for the Under at -105.

As always, make sure you check all the sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the White Sox (+1.5) are a 56% chance of covering the run line, while the Over/Under total of 8 runs is a 52% chance of going Over.

More: Best Free Bet Tracker

Best Bets for Astros vs. White Sox

• Run Line: White Sox +1.5 @ -130 via Caesars Sportsbook (56% probability)
• Moneyline: White Sox @ +130 via DraftKings Sportsbook (2.6% edge)
• Total: Over 8 @ -105 via PointsBet (52% probability)

Our best bets are based on complex simulations and betting intelligence to bring you the best possible plays every time.

While the Astros are more likely to win the game, according to DimersBOT, betting on the White Sox moneyline is the best option due to the 2.6% edge identified when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges published on Dimers.com is pivotal to being profitable in the long run.

Astros vs. White Sox Betting Guide

Use our dynamic widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for Houston vs. CHI White Sox, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Wednesday's Astros-White Sox matchup, including pregame predictions, top betting picks, and live win probabilities.

Remember, DimersBOT updates often, so keep checking this article for the latest betting insights before Astros vs. White Sox on Wednesday August 17, 2022.

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Note: When you click or tap on a link on Dimers that goes to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may get a referral fee.

Astros vs. White Sox 2022 Game Info

Wednesday's matchup between the White Sox and Astros at Guaranteed Rate Field is scheduled to begin at 8:10PM ET.

• Who: Chicago White Sox vs. Houston Astros
• Date: Wednesday August 17, 2022
• Time: 8:10PM ET / 5:10PM PT
• Venue: Guaranteed Rate Field

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What other MLB games are on today?

Now you've got the 411 on Astros vs. White Sox, see the latest betting predictions for all upcoming MLB games in our MLB Bet Hub, where you can find probabilities and odds, as well as our best bets for every single MLB matchup.

Want a pick for the Run Line? You got it. How about the Over/Under? Yup, got that too. The Moneyline? Yes sir. And these picks are good, I mean REALLY good. Take a look now!

Finally, Dimers' Baseball Futures page is our in-house approach to revealing who will win the 2022 World Series, with our data-led probabilities compared to the best odds available.