Astros vs. Twins Prediction and Odds - May 11, 2022

The Minnesota Twins and Houston Astros clash in MLB at Target Field on Wednesday, starting at 7:40PM ET.

Chris Archer (0-0, 3.26 ERA) will get the ball for the Twins, while the Astros will counter with José Urquidy (2-1, 4.56 ERA).

Dimers' best betting picks for Astros vs. Twins, plus game predictions and best odds, are detailed in this article.

Today's Houston vs. Minnesota betting analysis is sponsored by PointsBet, which has an awesome 5x $100 Risk-Free Bets offer for new users.

Who will win Astros vs. Twins?

Based on advanced computer power and data, Dimers.com has simulated Wednesday's Astros-Twins MLB matchup 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, currently gives the Astros a 52% chance of beating the Twins.

More: Full Betting Analysis for Astros vs. Twins

Astros vs. Twins Game Odds

• Run Line: Twins +1.5 (-160), Astros -1.5 (+145)
• Moneyline: Twins +105, Astros -118
• Total: Over/Under 8.5 (-110/+100)

Run Line, Moneyline and Over/Under

The Twins are +1.5 underdogs against the Astros, with -160 at PointsBet the best odds currently available.

For the favored Astros (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on offer at +145.

BetMGM currently has the best moneyline odds for the Twins at +105. That means you can bet $100 to profit $105, earning a total payout of $205, if they win.

On the other hand, FanDuel Sportsbook currently has the best moneyline odds for the Astros at -118, where you can risk $118 to win $100, for a total payout of $218, if they come out on top.

The Over/Under is set at 8.5 with DraftKings Sportsbook, which currently has the best odds for the Over at -110, while BetMGM currently has the best odds for the Under at +100.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Twins (+1.5) are a 61% chance of covering the run line, while the Over/Under total of 8.5 runs is a 53% chance of going Over.

More: Today's Best Bets for All Major Sports

Best Bets for Astros vs. Twins

• Run Line: Twins +1.5 @ -160 via PointsBet (61% probability)
• Moneyline: Twins @ +105 via BetMGM
• Total: Over 8.5 @ -110 via DraftKings Sportsbook (53% probability)

Dimers' best bets are based on complex simulations and betting intelligence to help you make smarter investments with the legal sportsbooks in the United States.

While the Astros are more likely to win the game, according to DimersBOT, taking the Twins moneyline is the best option due to the edge identified when comparing our data-led probabilities to the betting odds currently available.

Taking advantage of the edges published on Dimers.com is pivotal to achieving long-term profitability as a sports bettor.

Astros vs. Twins Betting Guide

Use our interactive widget below to see up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Houston vs. Minnesota, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Wednesday's Astros-Twins matchup, including pregame predictions, top betting picks, and live win probabilities.

Don't forget, DimersBOT updates often, so keep an eye on this page for any changes to our betting analysis ahead of Astros vs. Twins on Wednesday May 11, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Astros vs. Twins 2022 Game Info

Wednesday's matchup between the Twins and Astros at Target Field is scheduled to commence at 7:40PM ET.

• Date: Wednesday May 11, 2022
• Time: 7:40PM ET / 4:40PM PT
• Venue: Target Field

Looking to join an online sportsbook and start betting on MLB today? Check out the best sports betting sign-up offers in your state.

Want more MLB analysis like this?

So, you liked our Astros vs. Twins betting predictions? Awesome. Did you know our MLB Betting News section has a detailed betting preview for every MLB game the second the sportsbooks release their odds?

That's right, our predictive analytics model then compares those odds (aka Vegas odds) against its own probabilities to find edges in the markets, which allows us to create the most authoritative MLB betting previews and beat the public and the sportsbooks to the punch.

It's only a click away, so why not take a look around?

Lastly, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds available.