Astros vs. Rangers Prediction and Odds - Apr 27, 2022

MLB action continues on Wednesday at 8:05PM ET as the Houston Astros lock horns with the Texas Rangers at Globe Life Field.

Glenn Otto (1-0, 1.80 ERA) will start on the mound for the Rangers, pitting him against Cristian Javier (0-0, 0.00 ERA) for the Astros.

Dimers' top betting picks for Astros vs. Rangers, as well as game predictions and best odds, are detailed below.

Who will win Astros vs. Rangers?

Using state-of-the-art machine learning and data, Dimers.com has simulated Wednesday's Astros-Rangers MLB game 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, currently can't split the two teams, giving both the Astros and Rangers a 50% chance of winning the game.

More: Astros vs. Rangers Simulated 10,000 Times

Astros vs. Rangers Game Odds

• Run Line: Rangers +1.5 (-166), Astros -1.5 (+155)
• Moneyline: Rangers +100, Astros -110
• Total: Over/Under 8.5 (+100/-110)

Run Line, Moneyline and Over/Under

The Rangers are +1.5 underdogs versus the Astros, with -166 at FanDuel Sportsbook the best odds currently available.

For the favored Astros (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on the market at +155.

Caesars Sportsbook currently has the best moneyline odds for the Rangers at +100. That means you can risk $100 to win $100, for a total payout of $200, if they get the W.

Elsewhere, BetMGM currently has the best moneyline odds for the Astros at -110, where you can risk $110 to win $100, for a total payout of $210, if they come out on top.

The Over/Under sits at 8.5 with DraftKings Sportsbook, which currently has the best odds for the Over at +100, while Caesars Sportsbook currently has the best odds for the Under at -110.

As always, check out all the sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the Rangers (+1.5) are a 62% chance of covering the run line, while the 8.5-run Over/Under is a 52% chance of going Over.

More: Best Bets for Every MLB Matchup

Best Bets for Astros vs. Rangers

• Run Line: Rangers +1.5 @ -166 via FanDuel Sportsbook (62% probability)
• Moneyline: Rangers @ +100 via Caesars Sportsbook (50% probability)
• Total: Over 8.5 @ +100 via DraftKings Sportsbook (52% probability)

Dimers' best bets are based on complex simulations and betting intelligence to bring you the best possible plays 24/7.

Astros vs. Rangers Betting Guide

Use our dynamic widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Houston vs. Texas, and click or tap on See Matchup to reveal more.

Dimers has full coverage of Wednesday's Astros-Rangers matchup, including pregame predictions, computer picks, and live win probabilities.

Remember, DimersBOT updates regularly, so keep checking this article for any changes to our betting insights ahead of Astros vs. Rangers on Wednesday April 27, 2022.

Best Betting Promo for Astros vs. Rangers

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Astros vs. Rangers 2022 Game Info

When do the Rangers play the Astros?

• Date: Wednesday April 27, 2022
• Time: 8:05PM ET / 5:05PM PT
• Venue: Globe Life Field

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Want more MLB previews like this?

So, you liked our Astros vs. Rangers betting predictions? Awesome. Did you know our MLB Betting News section has a detailed betting preview for every MLB matchup as soon as the sportsbooks release their odds?

That's right, our predictive analytics model then compares those odds (aka Vegas odds) against its own probabilities to find value in the markets. This allows us to write the most authoritative MLB betting previews and get the jump on the public and the sportsbooks.

It's only a click away, so why not see for yourself?

While you're here, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities matched against the best odds to win the World Series.