Astros vs. Mariners Prediction and Odds - May 28, 2022

The Seattle Mariners square off with the Houston Astros in MLB action at T-Mobile Park on Saturday, starting at 10:10PM ET.

Logan Gilbert (4-2, 2.60 ERA) will be on the bump for the Mariners, while the Astros will counter with José Urquidy (4-1, 4.24 ERA).

Dimers' top betting picks for Astros vs. Mariners, plus game predictions and best odds, are featured below.

Today's Houston vs. Seattle betting preview is sponsored by PointsBet, which has an awesome 5x $100 Risk-Free Bets promo for new customers.

Who will win Astros vs. Mariners?

Based on cutting-edge computer power and data, Dimers.com has simulated Saturday's Astros-Mariners MLB matchup 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, gives the Astros a 55% chance of beating the Mariners.

More: Full Betting Analysis for Astros vs. Mariners

Astros vs. Mariners Current Odds

• Run Line: Mariners +1.5 (-161), Astros -1.5 (+150)
• Moneyline: Mariners +105, Astros -115
• Total: Over/Under 7.5 (-110/+100)

Run Line, Moneyline and Over/Under

The Mariners are +1.5 underdogs versus the Astros, with -161 at Caesars Sportsbook the best odds currently available.

For the favored Astros (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +150.

Caesars Sportsbook currently has the best moneyline odds for the Mariners at +105, which means you can throw down $100 to profit $105, earning a total payout of $205, if they win.

On the other hand, BetMGM currently has the best moneyline odds for the Astros at -115, where you can risk $115 to win $100, for a total payout of $215, if they come out on top.

The Over/Under for total runs scored sits at 7.5 with Caesars Sportsbook, which currently has the best odds for the Over at -110, while DraftKings Sportsbook currently has the best odds for the Under at +100.

As always, check out all the sportsbooks that are available in your state for the best MLB odds and lines.

According to DimersBOT, the Mariners (+1.5) are a 63% chance of covering the run line, while the Over/Under total of 7.5 runs is a 54% chance of going Over.

More: Best Free Bet Tracker

Best Bets for Astros vs. Mariners

• Run Line: Mariners +1.5 @ -161 via Caesars Sportsbook (63% probability)
• Moneyline: Astros @ -115 via BetMGM (55% probability)
• Total: Over 7.5 @ -110 via Caesars Sportsbook (54% probability)

Dimers' best bets are based on world-class simulations and wagering intelligence to help you make more informed investments with the legal sportsbooks in America.

Astros vs. Mariners Probabilities

Use our dynamic widget below to view the latest Moneyline, Over/Under and Run Line probabilities and odds for Houston vs. Seattle, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Saturday's Astros-Mariners matchup, including pregame predictions, computer picks, and live win probabilities.

Don't forget, DimersBOT updates frequently, so keep an eye on this article for the latest betting analysis before Astros vs. Mariners on Saturday May 28, 2022.

Best Betting Offer for Astros vs. Mariners

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Astros vs. Mariners 2022 Game Info

Saturday's matchup between the Mariners and Astros at T-Mobile Park is scheduled to start at 10:10PM ET.

• Who: Seattle Mariners vs. Houston Astros
• Date: Saturday May 28, 2022
• Time: 10:10PM ET / 7:10PM PT
• Venue: T-Mobile Park

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What MLB games are on today?

The Astros and Mariners aren't the only two MLB teams you can bet on. DimersBOT never stops and we've got picks and best bets for every single MLB game in our MLB Bet Hub section.

Not only do we provide with you quality predictions, but we also have recommended bets for the Run Line, Over/Under and Moneyline. Sound good? Check it out now!

Finally, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds on the market.