Astros vs. Mariners Prediction and Odds - Apr 15, 2022

The Seattle Mariners square off with the Houston Astros in MLB action at T-Mobile Park on Friday, commencing at 9:42PM EDT.

Marco Gonzales (0-1, 9.00 ERA) will be on the bump for the Mariners, pitting him against Jake Odorizzi (0-0, 4.50 ERA) for the Astros.

Dimers' free betting picks for Astros vs. Mariners, plus game predictions and best odds, are featured below.

Who will win Astros vs. Mariners?

Based on trusted machine learning and data, Dimers.com has simulated Friday's Astros-Mariners MLB matchup 10,000 times.

Dimers' proven predictive analytics model, DimersBOT, currently gives the Astros a 59% chance of defeating the Mariners.

More: Free Betting Analysis for Astros vs. Mariners

Astros vs. Mariners Current Odds

• Run Line: Mariners +1.5, Astros -1.5
• Moneyline: Mariners +100, Astros -115
• Total: Over/Under 8

Run Line, Moneyline and Over/Under

The Mariners are +1.5 underdogs versus the Astros, with -160 at BetMGM the best odds currently available.

For the favored Astros (-1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on the market at +140.

BetMGM currently has the best moneyline odds for the Mariners at +100. That means you can risk $100 to win $100, for a total payout of $200, if they get the W.

Meanwhile, Caesars Sportsbook currently has the best moneyline odds for the Astros at -115, where you can risk $115 to win $100, for a total payout of $215, if they come out on top.

The Over/Under for total runs scored sits at 8 with Caesars Sportsbook, which currently has the best odds for the Over at -105, while BetMGM currently has the best odds for the Under at +100.

As always, check out the sportsbooks you have access to in your state for the best MLB odds and lines.

According to DimersBOT, the Mariners (+1.5) are a 59% chance of covering the run line, while the Over/Under total of 8 runs is a 54% chance of going Over.

More: Best Bets Today for All Major Sports

Best Bets for Astros vs. Mariners

• Run Line: Astros -1.5 @ +140 via DraftKings Sportsbook
• Moneyline: Astros @ -115 via Caesars Sportsbook (59% probability) 🔥
• Total: Over 8 @ -105 via Caesars Sportsbook (54% probability)

When you see a 🔥, you know it's one of Dimers' best bets today across all sports.

Dimers' best bets are based on world-class simulations and wagering intelligence to help you make more informed decisions with the legal sportsbooks in America.

Although the Mariners are more likely to cover the run line, our best bet of Astros -1.5 is based on the expectation of that happening, according to DimersBOT, and the best odds available.

Astros vs. Mariners Betting Guide

Use our widget below to view up-to-date Moneyline, Over/Under and Run Line probabilities and odds for Houston vs. Seattle, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Friday's Astros-Mariners matchup, including pre-game predictions, free betting picks, and live win probabilities.

Don't forget, DimersBOT updates regularly, so check this page for the latest betting analysis ahead of Astros vs. Mariners on Friday April 15, 2022.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Astros vs. Mariners 2022 Game Info

When do the Mariners play the Astros?

• Date: Friday April 15, 2022
• Time: 9:42PM EDT / 6:42PM PDT
• Venue: T-Mobile Park

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Want more MLB previews like this?

So, you liked our Astros vs. Mariners betting analysis? Awesome. Did you know our MLB Betting News page has a comprehensive betting preview for every MLB matchup the second the sportsbooks put out their odds?

That's right, our predictive analytics model then compares those odds (aka Vegas odds) against its own probabilities to find value in the markets. This allows us to create the most reliable MLB betting previews and beat the public and the sportsbooks to the punch.

It's only a click away, so why not see for yourself?

While you're here, Dimers' Baseball Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.