Astros vs. D-Backs Prediction and Odds - Apr 12, 2022

The Arizona D-Backs square off with the Houston Astros in MLB action at Chase Field on Tuesday, commencing at 9:40PM EDT.

The D-Backs will have Madison Bumgarner (0-0, 3.00 ERA) start, up against Luis Garcia (0-0, 0.00 ERA) for the Astros.

Dimers' free betting picks for Astros vs. D-Backs, plus game predictions and best odds, are featured in this article.

Who will win Astros vs. D-Backs?

Using cutting-edge computer power and data, Dimers.com has simulated Tuesday's Astros-D-Backs MLB matchup 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently gives the Astros a 60% chance of defeating the D-Backs.

More: Full Betting Guide for Astros vs. D-Backs

Astros vs. D-Backs Game Odds

• Run Line: D-Backs +1.5, Astros -1.5
• Moneyline: D-Backs +140, Astros -144
• Total: Over/Under 9

Run Line, Moneyline and Over/Under

The D-Backs are +1.5 underdogs versus the Astros, with -120 at BetMGM the best odds currently available.

For the favored Astros (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +116.

Caesars Sportsbook currently has the best moneyline odds for the D-Backs at +140. That means you can throw down $100 to profit $140, earning a total payout of $240, if they win.

Elsewhere, FanDuel Sportsbook currently has the best moneyline odds for the Astros at -144, where you can risk $144 to win $100, for a total payout of $244, if they come out on top.

The Over/Under is set at 9 with DraftKings Sportsbook, which currently has the best odds for the Over at -110, while BetMGM currently has the best odds for the Under at +100.

As always, make sure you check all the sportsbooks available in your state for the best MLB odds and lines.

According to DimersBOT, the D-Backs (+1.5) are a 52% chance of covering the run line, while the 9-run Over/Under is a 56% chance of going Over.

More: Best Bets for Every MLB Matchup

Best Bets for Astros vs. D-Backs

• Run Line: Astros -1.5 @ +116 via FanDuel Sportsbook (2.0% edge)
• Moneyline: Astros @ -144 via FanDuel Sportsbook (60% probability)
• Total: Over 9 @ -110 via DraftKings Sportsbook (56% probability)

Dimers' best bets are based on detailed simulations and betting intelligence to serve you the best possible plays every time.

Although the D-Backs are more likely to cover the run line, our best bet of Astros -1.5 is based on the chance of that happening, according to DimersBOT, and the top odds available.

Astros vs. D-Backs Betting Guide

Use our dynamic widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for Houston vs. Arizona, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of Tuesday's Astros-D-Backs matchup, including pre-game predictions, best betting picks, and live win probabilities.

Remember, DimersBOT updates often, so keep checking this article for any changes to our betting analysis before Astros vs. D-Backs on Tuesday April 12, 2022.

Best Sportsbook Promo for Astros vs. D-Backs

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Astros vs. D-Backs 2022 Game Info

When do the D-Backs play the Astros?

• Date: Tuesday April 12, 2022
• Time: 9:40PM EDT / 6:40PM PDT
• Venue: Chase Field

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Want more MLB previews like this?

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We use the power of predictive analytics to find edges in the markets so we can publish the best MLB betting previews out there. We do this by comparing our in-house probabilities against the sportsbooks' odds (aka Vegas odds) as soon as they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.

Lastly, Dimers' MLB Futures page is our in-house approach to determining who will win the 2022 World Series, with our data-led probabilities compared to the best odds to win the World Series.