Astros vs. Angels Prediction and Odds - Apr 7, 2022

The Los Angeles Angels face the Houston Astros on Opening Day of the 2022 MLB season at Angel Stadium on Thursday, starting at 9:38PM EDT.

Shohei Ohtani (0-0, 0.00 ERA) will get the ball for the Angels, up against Framber Valdez (0-0, 0.00 ERA) for the Astros.

Dimers' free betting picks for Astros vs. Angels, as well as game predictions and best odds, are detailed in this article.

Who will win Astros vs. Angels?

Based on advanced computer power and data, Dimers.com has simulated Thursday's Astros-Angels MLB matchup 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, currently gives the Angels a 52% chance of winning against the Astros.

MORE: Astros vs. Angels Simulated 10K Times

Run Line, Moneyline and Over/Under

The Angels are listed as -1.5 favorites against the Astros, with +155 at BetMGM the best odds currently available.

For the underdog Astros (+1.5) to cover the run line, DraftKings Sportsbook has the best odds currently on the market at -170.

BetMGM currently has the best moneyline odds for the Angels at -120, which means you can risk $120 to win $100, for a total payout of $220, if they get the W.

Meanwhile, FanDuel Sportsbook currently has the best moneyline odds for the Astros at +108, where you can bet $100 to profit $108, earning a total payout of $208, if they win.

The Over/Under sits at 8.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -118, while Caesars Sportsbook currently has the best odds for the Under at +100.

As always, make sure you check the sportsbooks you can bet with in your state for the best MLB odds and lines.

According to DimersBOT, the Astros (+1.5) are a 65% chance of covering the run line, while the 8.5-run Over/Under is a 53% chance of going Over.

MORE: Best Bets Today for All Major Sports

Best Bets for Astros vs. Angels

• Run Line: Astros +1.5 @ -170 via DraftKings Sportsbook (65% probability)
• Moneyline: Astros @ +108 via FanDuel Sportsbook (0.2% edge)
• Over/Under: Over 8.5 @ -118 via FanDuel Sportsbook (53% probability)

Dimers' best bets are based on detailed simulations and betting intelligence to serve you the best possible plays every time.

While the Angels are more likely to win the game, according to DimersBOT, betting on the Astros moneyline is the best option because of the edge identified when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges published on Dimers.com is pivotal to being profitable in the long run.

Astros vs. Angels Probabilities

Use our interactive widget below to explore the latest Moneyline, Over/Under and Run Line probabilities and odds for Houston vs. LA Angels, and click or tap on See Matchup for more.

Dimers has full coverage of Thursday's Astros-Angels matchup, including pre-game predictions, top betting picks, and live updates.

Don't forget, DimersBOT updates often, so check this page for any changes to our betting analysis ahead of Astros vs. Angels on Thursday April 7, 2022.

Best Betting Offer for Astros vs. Angels

Do you want to bet on Houston vs. LA Angels? Join FanDuel Sportsbook now and get your first bet risk free up to $1,000, which you can use on Thursday's Astros-Angels matchup.

Simply click or tap on this exclusive FanDuel Sportsbook link and create a new account – it's easy and takes less than 2 minutes.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

Astros vs. Angels 2022 Game Info

When do the Angels play the Astros?

• Date: Thursday April 7, 2022
• Time: 9:38PM EDT / 6:38PM PDT
• Venue: Angel Stadium

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Want more MLB previews like this?

To get more MLB betting previews like you've just read for Astros vs. Angels, all you've gotta do is visit Dimers' MLB Betting News section. It's that easy – they're all there!

We use the power of predictive analytics to find value in the markets so we can produce the best MLB betting previews out there. We're able to do this by comparing our own probabilities against the sportsbooks' odds (aka Vegas odds) the minute they go live.

So, get ahead of the game and beat the 'books today – it's only a click away.