Arkansas-Pine Bluff vs. DePaul prediction: DePaul favored to win men's college basketball matchup [12/6/2025]

DePaul and Arkansas-Pine Bluff are scheduled to meet in men's college basketball action at Wintrust Arena on Saturday, with tipoff at 9:00PM ET.

Based on updated simulation results, Dimers' proven college basketball model projects DePaul as the most likely winner of the Arkansas-Pine Bluff vs. DePaul game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Arkansas-Pine Bluff vs. DePaul prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Saturday's NCAA basketball game between Arkansas-Pine Bluff and DePaul 10,000 times as part of our men's college basketball predictions coverage.

Our independent predictive model gives DePaul a 97% chance of beating Arkansas-Pine Bluff. Our predicted final score has DePaul winning 88-65.

According to our model, Arkansas-Pine Bluff (+23.5) has a 52% chance of covering the spread, while the 155.5-point over/under has a 52% chance of staying under.

Arkansas-Pine Bluff vs. DePaul odds

We have sourced the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Arkansas-Pine Bluff vs. DePaul picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: