Arizona Cardinals vs. Chicago Bears Prediction, Odds, NFL Picks - Week 16 [2023]

Arizona Cardinals vs. Chicago Bears Prediction, Odds, NFL Picks - Week 16 [2023]

The Chicago Bears and Arizona Cardinals will lock horns in Week 16 of the NFL season at Soldier Field on Sunday, with kickoff at 4:25PM ET.'s full betting preview for Sunday's Cardinals vs. Bears matchup includes the latest betting odds, as well as our predictions and picks for the game.

Cardinals vs. Bears Prediction: Who Will Win, Cover the Spread

We have used innovative machine learning and statistics to simulate the outcome of Sunday's NFL matchup between the Cardinals and Bears 10,000 times, in line with our coverage of NFL predictions.

Our popular predictive analytics model currently gives the Bears a 65% chance of beating the Cardinals in Week 16 of the NFL season, and our predicted final score has the Bears winning 22-19.

According to our model, the Cardinals (+4.5) have a 54% chance of covering the spread, while the Over/Under total of 42 points has an equal 50-50 chance of hitting.

This Arizona vs. Chicago betting preview is sponsored by Bet365, which has an outstanding Bet $5, Get $150 in Bonus Bets offer for new users.

Cardinals vs. Bears Odds

We have researched the best betting odds in America for this game, which are listed here:

Bet Type Cardinals Bears
Spread +4.5 (-110) -4.5 (-110)
Moneyline +180 -215
Total o42 (-115) u42 (-105)
  • The Bears are -4.5 favorites versus the Cardinals, with -110 at BetMGM Sportsbook the best odds currently available.
  • For the underdog Cardinals (+4.5) to cover the spread, BetMGM also has the best odds currently on offer at -110.
  • FanDuel Sportsbook currently has the best moneyline odds for the Bears at -215, which means you can risk $215 to win $100 for a total payout of $315 if they get the W.
  • On the other hand, BetMGM currently has the best moneyline odds for the Cardinals at +180, where you can put down $100 to profit $180, earning a total payout of $280 if they win.
  • The Over/Under for total points scored sits at 42 with DraftKings Sportsbook, which currently has the best odds for the Over at -115, as well as the best odds for the Under at -105.

All odds are correct at the time of publication and are subject to change.

As always, check out the sports betting sites you can bet with in your state for the best NFL odds and lines.

Cardinals vs. Bears Picks

By comparing our predictions to the odds listed above, we have determined the best betting picks to place on this game:

Bet Type Our Pick Best Odds
Spread Cardinals +4.5 -110
Moneyline Cardinals +180
Total Under 42 -105


While the Bears are more likely to win the game, betting on the Cardinals moneyline is the best option because of the edge found when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published here at Dimers is pivotal to being profitable in the long run.

Dimers' NFL best bets are based on world-class simulations and betting intelligence to bring you the best possible plays every week of the season.

Calling all football fans! If you are yet to sign up with DraftKings Sportsbook, today is the day! Click here to sign up, and then place a $5 wager on Arizona vs. Chicago to receive $150 in bonus bets, win or lose!

Cardinals vs. Bears TD Scorers

Who will score an anytime touchdown in Cardinals vs. Bears?

According to our model, Chicago's Justin Fields is most likely to score the first touchdown in Cardinals vs. Bears.

Our projections give Fields a 14.0% chance of scoring the first TD at Soldier Field, while the Bears QB is a 51.3% chance of scoring an anytime touchdown.

First Touchdown Scorer Predictions

Arizona Cardinals

Player First TD Probability
James Conner 9.2%
Trey McBride 6.9%
Kyler Murray 6.0%
Greg Dortch 5.1%
Rondale Moore 4.0%

Chicago Bears

Player First TD Probability
Justin Fields 14.0%
DJ Moore 9.5%
Roschon Johnson 9.5%
Cole Kmet 7.8%
Khalil Herbert 6.9%

Anytime Touchdown Scorer Predictions

Arizona Cardinals

Player Anytime TD Probability
James Conner 39.0%
Trey McBride 29.3%
Kyler Murray 26.9%
Greg Dortch 22.5%
Elijah Higgins 18.2%

Chicago Bears

Player Anytime TD Probability
Justin Fields 51.3%
Roschon Johnson 39.6%
DJ Moore 38.4%
Cole Kmet 32.7%
Khalil Herbert 29.6%

Cardinals vs Bears Player Props

Here, you will find detailed projections for all of the key offensive players from the Cardinals and Bears, including passing, rushing and receiving yards.

Cardinals vs. Bears Quarterbacks

Of the starting quarterbacks, the Cardinals' Kyler Murray is projected for 194 passing yards. The Bears' Justin Fields is expected to throw for 230 yards.

Player Proj. Pass Yards
Kyler Murray (ARI) 194 yds
Justin Fields (CHI) 230 yds

Cardinals Rushing

Player Proj. Rush Yards
James Conner 75 yds
Kyler Murray 26 yds
Michael Carter 13 yds

Bears Rushing

Player Proj. Rush Yards
Justin Fields 72 yds
Khalil Herbert 51 yds
Roschon Johnson 30 yds

Cardinals Receiving

Player Proj. Rec. Yards
Trey McBride 55 yds
Greg Dortch 39 yds
Michael Wilson 34 yds
Rondale Moore 29 yds
Elijah Higgins 18 yds

Bears Receiving

Player Proj. Rec. Yards
DJ Moore 87 yds
Cole Kmet 50 yds
Darnell Mooney 33 yds
Roschon Johnson 19 yds
Tyler Scott 13 yds

Don't forget, our model updates regularly, so keep checking this article for any changes to our betting insights ahead of the Cardinals vs. Bears on Sunday December 24, 2023.

Cardinals vs. Bears Game Information

The NFL Week 16 matchup between the Bears and Cardinals at Soldier Field is scheduled to commence at 4:25PM ET.


Our full coverage of Cardinals vs. Bears includes pregame predictions, betting picks, and live win probabilities.

How to Bet on Cardinals vs. Bears

Looking to join an online sportsbook and start betting on the NFL? We've listed the best available welcome offers in each legal betting state, including Bet365, where you get $150 in bonus bets for signing up and bettting $5 on Arizona vs. Chicago.


This preview article has been partially generated using automated processes and AI technology. Our goal is to provide timely and accurate updates on Cardinals vs. Bears Week 14 contest, and automation assists in data collection, analysis, and formatting. Human editing and quality control are performed to ensure the content meets our editorial standards.

Dimers' predictions are made thanks to 10,000 simulations per game, using reliable and up-to-date data sources and analytical methods. While these Cardinals vs. Bears picks can help you make informed decisions, it's crucial that you gamble responsibly and manage your bankroll effectively.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

When you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may receive a referral fee at no additional cost to you.

More on NFL

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Ryan Leaver
Senior Sports and Sports Betting Editor

Ryan Leaver has long been entrenched in the world of sports and sports betting, now specializing in the NBA, NFL, college football, college basketball, and soccer. His passion shines through in his detailed game previews, best bets, props, and futures articles for both the NBA and NFL, along with his sharp prop bets for college football and insightful best bets for college basketball. Ryan’s expertise also extends to soccer, where he frequently offers practical betting tips and highlights the bets of the day. 

Known for his keen eye for valuable betting promos, Ryan adeptly guides bettors toward opportunities that enhance their wagering experiences. Collaborating often with DimersBOT, his articles are meticulously researched and offer savvy betting advice, making him a trusted source for sports bettors.

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