American University vs. VCU prediction: Virginia Commonwealth favored to win men's college basketball matchup [12/18/2025]

VCU will square off with American University in men's college basketball action at Stuart C. Siegel Center on Thursday, starting at 7:00 PM ET.

Based on the latest simulations, Dimers' proven college basketball model projects Virginia Commonwealth as the most likely winner of the American University vs. VCU game.

This article offers further insights into Thursday's matchup, including an expanded look at the predicted score, best bets and picks.

American University vs. VCU prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the result of Thursday's NCAA basketball matchup between American University and VCU 10,000 times as part of our men's college basketball predictions coverage.

Our famous predictive model gives Virginia Commonwealth a 96% chance of beating American University. Our predicted final score has Virginia Commonwealth winning 88-66.

According to our model, Virginia Commonwealth (-19.5) has a 53% chance of covering the spread, while the 155.5-point over/under has an equal 50-50 chance of hitting.

American University vs. VCU odds

We have researched the best men's college basketball odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

American University vs. VCU picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: