Alexei Popyrin vs. Daniil Medvedev Prediction, Odds, Picks for ATP Italian Open 2025

Alexei Popyrin will square off with Daniil Medvedev in the round of 32 at the ATP Rome event on Sunday.

Based on the latest simulation results, Dimers' proven tennis model (see Dimers Pro for full access) predicts Daniil Medvedev as the most likely winner of the match.

"Using the most recent data, we ran 10,000 simulations of Sunday's Popyrin-Medvedev match," said Dimers data analyst Greg Butyn.

"After accounting for recent updates and other variables, our prediction shows Daniil Medvedev with a win probability of 64%, while Alexei Popyrin has 36%."

For a closer look at Sunday's match, including best bets and picks, visit our interactive Popyrin vs. Medvedev predictions page.

Popyrin vs. Medvedev Prediction: Who Will Win and Advance to the Round of 16?

Using innovative machine learning and data, we have simulated the outcome of Sunday's Popyrin-Medvedev men's singles match 10,000 times as part of our tennis predictions coverage.

Our leading predictive model currently gives Medvedev a 64% chance of beating Popyrin at the ATP Italian Open tournament.

Additionally, Medvedev has a 60% chance of winning the first set, according to our model.

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Alexei Popyrin vs. Daniil Medvedev Odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Popyrin	Medvedev
Moneyline	+220	-278
First Set	+162	-200

All odds are correct at the time of publication and are subject to change.

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Popyrin vs. Medvedev Picks and Best Bets

Our model's biggest edge in today's Popyrin vs. Medvedev match is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best tennis picks and tennis best bets for every match throughout the year.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Popyrin vs. Medvedev Updates and Essential Details

The ATP Italian Open match between Alexei Popyrin and Daniil Medvedev is scheduled to begin on Sunday at 5:00AM ET.

• Who: Alexei Popyrin vs. Daniil Medvedev
• Date: Sunday, May 11, 2025
• Approx. Time: 5:00AM ET/2:00AM PT
• Tournament: ATP Rome, Italy Men's Singles 2025
• Round: Round of 32

All dates and times in this article are United States Eastern Time unless otherwise noted.

Dimers.com's in-depth preview of Sunday's Popyrin vs. Medvedev match includes our prediction, picks and the latest betting odds.

Before making any Alexei Popyrin vs. Daniil Medvedev picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

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• Explore where sports odds come from and how they’re applied to tennis matches
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• Improve your chances with proven sports betting strategies that apply to tennis and more

Conclusion

We predict Daniil Medvedev, with a 64% win probability, will likely beat Alexei Popyrin at the ATP Italian Open tournament.

AI and automation have enhanced this article to quickly deliver accurate Popyrin vs. Medvedev insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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