49ers vs. Rams Predictions and Odds - Jan 30, 2022

The Los Angeles Rams square off with the San Francisco 49ers in the NFC Championship Game of the 2021 NFL Playoffs at SoFi Stadium on Sunday, commencing at 6:30PM EST.

Dimers' best betting picks for 49ers vs. Rams, plus game predictions, best odds and player props, are featured below.

This San Francisco vs. LA Rams betting analysis is sponsored by FanDuel Sportsbook, which has a Bet $5, Win $150 offer for new customers during this year's NFL Playoffs.

Who will win San Francisco vs. LA Rams?

Using cutting-edge computer power and data, Dimers.com has simulated Sunday's 49ers-Rams NFL matchup 10,000 times.

Dimers' revolutionary predictive analytics model, DimersBOT, currently gives the Rams a 60% chance of defeating the 49ers.

MORE: Free Betting Guide for 49ers vs. Rams

Point Spread, Moneyline and Over/Under

The Rams are -3.5 favorites against the 49ers, with -105 at PointsBet the best odds currently available.

For the underdog 49ers (+3.5) to cover the spread, BetMGM has the best odds currently on offer at -110.

BetMGM currently has the best moneyline odds for the Rams at -175. That means you can risk $175 to win $100, for a total payout of $275, if they get the W.

Meanwhile, DraftKings Sportsbook currently has the best moneyline odds for the 49ers at +155, where you can put down $100 to profit $155, earning a total payout of $255, if they win.

The Over/Under sits at 45.5 with Caesars Sportsbook, which currently has the best odds for the Over at -110, while DraftKings Sportsbook currently has the best odds for the Under at -105.

As always, make sure you check the sportsbooks you can bet with in your state for the best NFL odds and lines.

According to DimersBOT, the 49ers (+3.5) are a 59% chance of covering the spread, while the Over/Under total of 45.5 points is considered an equal 50-50 chance of hitting.

MORE: Predictions for Every NFL Game

Best Bets for 49ers vs. Rams

• Spread: 49ers +3.5 at -110 with BetMGM (59% probability) 🔥
• Moneyline: 49ers at +155 with DraftKings Sportsbook (1.2% edge)
• Over/Under: Under 45.5 at -105 with DraftKings Sportsbook (50% probability)

Every time you see a 🔥, that means it's one of our best bets of the day across any sport.

Dimers' best bets are based on detailed simulations and wagering intelligence to serve you the best possible plays 24/7.

While the Rams are more likely to win the game, according to DimersBOT, taking the 49ers moneyline is the best option due to the 1.2% edge identified when comparing our data-led probabilities to the betting odds currently on offer.

Taking advantage of the edges seen on Dimers.com is crucial to being profitable in the long run.

San Francisco vs. LA Rams Score Prediction

Dimers.com's predicted final score for San Francisco vs. LA Rams at SoFi Stadium this Sunday has the Rams prevailing 23-21.

Use our interactive widget below to see the latest Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup to reveal more.

Dimers has full betting coverage of this week's 49ers-Rams matchup, including pre-game predictions, best betting picks, and live win probabilities.

49ers vs. Rams Player Props

Who will score the first touchdown in 49ers vs. Rams? The data is in.

Featured below are the most likely first touchdown and most likely anytime touchdown scorers for both the 49ers and Rams, as well as projected player stats.

And you know what, we provide this information to you for FREE to help you choose the best prop picks for Sunday's game.

According to DimersBOT, Los Angeles' Los D/ST is most likely to score the first touchdown in 49ers vs. Rams.

DimersBOT gives D/ST a 2.0% chance of scoring the first TD at SoFi Stadium, while the Rams D is a 4.0% chance of scoring an anytime touchdown.

First Touchdown Scorer Probabilities

San Francisco 49ers

• Mohamed Sanu: 2.0% probability
• Elijah Mitchell: 2.0% probability
• Robbie Gould: 2.0% probability
• Jimmy Garoppolo: 2.0% probability
• Brian Hill: 2.0% probability

Los Angeles Rams

• Los D/ST: 2.0% probability
• Buddy Howell: 2.0% probability
• Cam Akers: 2.0% probability
• Kendall Blanton: 2.0% probability
• Matthew Stafford: 2.0% probability

Anytime Touchdown Scorer Probabilities

San Francisco 49ers

• Mohamed Sanu: 4.0% probability
• Elijah Mitchell: 4.0% probability
• Robbie Gould: 4.0% probability
• Jimmy Garoppolo: 4.0% probability
• Brian Hill: 4.0% probability

Los Angeles Rams

• Los D/ST: 4.0% probability
• Buddy Howell: 4.0% probability
• Cam Akers: 4.0% probability
• Kendall Blanton: 4.0% probability
• Matthew Stafford: 4.0% probability

Projected Box Score

Of the starting quarterbacks, the 49ers' Jimmy Garoppolo is projected for 234 passing yards and 1.3 passing touchdowns, while the Rams' Matthew Stafford is expected to throw for a whopping 273 yards and 1.9 TDs.

49ers Starting QB

• Jimmy Garoppolo: 234 Passing Yards, 1.3 Passing TDs

Rams Starting QB

• Matthew Stafford: 273 Passing Yards, 1.9 Passing TDs

49ers Rushing

• Elijah Mitchell: 84 Rushing Yards, 0.4 TDs
• Deebo Samuel: 46 Rushing Yards, 0.5 TDs
• Jimmy Garoppolo: 7 Rushing Yards, 0.1 TDs

Rams Rushing

• Cam Akers: 72 Rushing Yards, 0.5 TDs
• Sony Michel: 17 Rushing Yards, 0.1 TDs
• Darrell Henderson: 9 Rushing Yards, 0.1 TDs

49ers Receiving

• Deebo Samuel: 74 Receiving Yards, 0.3 TDs
• George Kittle: 57 Receiving Yards, 0.3 TDs
• Brandon Aiyuk: 45 Receiving Yards, 0.2 TDs
• Jauan Jennings: 28 Receiving Yards, 0.2 TDs
• Elijah Mitchell: 14 Receiving Yards, 0.1 TDs

Rams Receiving

• Cooper Kupp: 102 Receiving Yards, 0.7 TDs
• Odell Beckham: 47 Receiving Yards, 0.4 TDs
• Van Jefferson: 43 Receiving Yards, 0.2 TDs
• Tyler Higbee: 38 Receiving Yards, 0.3 TDs
• Cam Akers: 14 Receiving Yards, 0.1 TDs

Don't forget, DimersBOT updates regularly, so keep an eye on this article for any changes to our betting insights ahead of 49ers vs. Rams on Sunday January 30, 2022.

Get 30/1 Odds on 49ers or Rams to Win

FanDuel Sportsbook has come to the party for the NFL Playoffs with 30/1 odds on either the 49ers or Rams to win on Sunday.

Simply join FanDuel Sportsbook using this exclusive link, make a first deposit of $10+, and place – as your first real-money wager – a $5 bet on either the 49ers or Rams to win at SoFi Stadium.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.

49ers vs. Rams 2022 Game Info

When do the Rams play the 49ers?

• Date: Sunday January 30, 2022
• Time: 6:30PM EST / 3:30PM PST
• Venue: SoFi Stadium

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What other NFL games are on tonight?

The 49ers and Rams aren't the only two NFL teams you can bet on today. DimersBOT never stops and we've got picks and best bets for every single NFL matchup via our NFL Predictions section.

Not only do we provide with you great predictions, but we also have recommended bets for the Spread, Over/Under and Moneyline. Sound good? Hell yeah it does!

Finally, get your Super Bowl party started right with our free Super Bowl Squares template, which you can download and print at home ahead of the Big Game.