Duke vs. South Carolina Prediction, Picks and Odds

Duke vs. South Carolina: Detailed Breakdown

Matchup Overview

• Teams: Duke vs. South Carolina
• Date: Wednesday, November 26, 2025
• Time: 4:30 PM ET
• Venue: Michelob ULTRA Arena

Current Betting Odds

• Spread: South Carolina favored at -17.5
• Total (Over/Under): 132.5
• Moneyline Odds: Duke +1500, South Carolina -2381

Dimers' Win Probabilities

• Duke: 10%
• South Carolina: 90%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this Women's College Basketball matchup is Duke 56-68 South Carolina.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives Duke a win probability of 10%, while South Carolina has a win probability of 90%.

Summary

According to our analysis, South Carolina is more likely to beat Duke in CBB action at Michelob ULTRA Arena on Wednesday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our Duke vs. South Carolina predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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