USC vs. Notre Dame Prediction, Picks and Odds

USC vs. Notre Dame: Detailed Breakdown

Matchup Overview

• Teams: USC vs. Notre Dame
• Date: Friday, November 21, 2025
• Time: 6:00 PM ET
• Venue: Purcell Pavilion

Current Betting Odds

• Spread: USC favored at -1.5
• Total (Over/Under): 143.5
• Moneyline Odds: USC +108, Notre Dame -110

Dimers' Win Probabilities

• USC: 43%
• Notre Dame: 57%

Dimers' predictive model estimates win probabilities after simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view of each team's chances.

Projected Final Score

Our predicted final score for this Women's College Basketball matchup is USC 71-73 Notre Dame.

This prediction is based on each team's average score following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives USC a win probability of 43%, while Notre Dame has a win probability of 57%.

Summary

According to our analysis, Notre Dame is more likely to beat USC in CBB action at Purcell Pavilion on Friday. Discover the best spread, over/under and moneyline odds, picks and probabilities for the game on this page.

Our USC vs. Notre Dame predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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