49ers vs. Packers Prediction, Picks and Odds

Our detailed prediction and analysis for the 49ers vs. Packers NFL game on January 22, 2022 is featured below. Drawing from 10,000 game simulations, we provide expert picks, betting odds, and insights.

Detailed Breakdown: 49ers vs. Packers

Matchup Overview

  • Teams: 49ers vs. Packers
  • Date: Saturday, January 22, 2022
  • Time: 8:15 PM ET
  • Venue: Lambeau Field

Current Betting Odds

  • Spread: Packers favored at -5.5
  • Total (Over/Under): 47.5
  • Moneyline Odds: 49ers +210, Packers -250

Win Probabilities

  • 49ers: 31%
  • Packers: 69%

Dimers.com's predictive model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Projected Final Score

Our predicted final score for this NFL matchup is 49ers 21-27 Packers.

This prediction is based on each team's average score following 10,000 game simulations.

Final Prediction: Who Wins?

After extensive simulations, our model gives the 49ers a win probability of 31%, while the Packers have a win probability of 69%. Discover the best spread, over/under, and moneyline odds for the game on this page.


Our 49ers vs. Packers predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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For further insights, explore our expert NFL predictions and the best NFL bets today, while our in-depth analysis includes NFL props, NFL futures, NFL odds, and the latest NFL news.

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