MLB- More Betting
White Sox vs. Tigers Prediction and Odds - Apr 8, 2022

The Detroit Tigers and Chicago White Sox lock horns in the MLB at Comerica Park on Friday, starting at 1:10PM EDT.
The Tigers will send Eduardo Rodríguez (0-0, 0.00 ERA) to the mound, while the White Sox are going with Lucas Giolito (0-0, 0.00 ERA).
Dimers' top betting picks for White Sox vs. Tigers, plus game predictions and best odds, are featured in this article.
Who will win White Sox vs. Tigers?
Using advanced computer power and data, Dimers.com has simulated Friday's White Sox-Tigers MLB matchup 10,000 times.
Dimers' revolutionary predictive analytics model, DimersBOT, gives the White Sox a 54% chance of winning against the Tigers.
MORE: White Sox vs. Tigers Simulated 10,000 Times
Run Line, Moneyline and Over/Under
The Tigers are +1.5 underdogs against the White Sox, with -145 at Caesars Sportsbook the best odds currently available.
For the favored White Sox (-1.5) to cover the run line, FanDuel Sportsbook has the best odds currently on offer at +128.
PointsBet currently has the best moneyline odds for the Tigers at +120. That means you can throw down $100 to profit $120, earning a total payout of $220, if they win.
Meanwhile, BetMGM currently has the best moneyline odds for the White Sox at -135, where you can risk $135 to win $100, for a total payout of $235, if they come out on top.
The Over/Under sits at 7.5 with FanDuel Sportsbook, which currently has the best odds for the Over at -114, while PointsBet currently has the best odds for the Under at -105.
As always, check out the sportsbooks you can bet with in your state for the best MLB odds and lines.
According to DimersBOT, the Tigers (+1.5) are a 60% chance of covering the run line, while the Over/Under total of 7.5 runs is a 56% chance of going Over.
MORE: Today's Best Bets for All Major Sports
Best Bets for White Sox vs. Tigers
- Run Line: Tigers +1.5 @ -145 via Caesars Sportsbook (60% probability)
- Moneyline: Tigers @ +120 via PointsBet (1.0% edge)
- Over/Under: Over 7.5 @ -114 via FanDuel Sportsbook (56% probability)
Dimers' best bets are based on complex simulations and betting intelligence to bring you the best possible plays every day of the year.
While the White Sox are more likely to win the game, according to DimersBOT, taking the Tigers moneyline is the best option due to the 1.0% edge identified when comparing our data-led probabilities to the sportsbooks' odds currently on offer.
Taking advantage of the edges seen on Dimers is pivotal to being a profitable sports bettor in the long run.
White Sox vs. Tigers Probabilities
Use our dynamic widget below to explore up-to-date Moneyline, Over/Under and Run Line probabilities and odds for CHI White Sox vs. Detroit, and click or tap on See Matchup to reveal more.
Dimers has full betting coverage of Friday's White Sox-Tigers matchup, including pre-game predictions, free betting picks, and live win probabilities.
Remember, DimersBOT updates frequently, so keep checking this page for the latest betting insights before White Sox vs. Tigers on Friday April 8, 2022.
Claim Your Risk-Free Bet for White Sox vs. Tigers
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Simply click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.
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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.
White Sox vs. Tigers 2022 Game Info
When do the Tigers play the White Sox?
- Date: Friday April 8, 2022
- Time: 1:10PM EDT / 10:10AM PDT
- Venue: Comerica Park
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