Blue Jays vs. Cardinals Prediction: St. Louis Predicted to Win Wednesday's MLB Matchup [6/11/2025]

The St. Louis Cardinals will take on the Toronto Blue Jays in MLB action at Busch Stadium on Wednesday, beginning at 2:15PM ET.

The Cardinals will send Matthew Liberatore (3-5, 3.82 ERA) to the mound, while the Blue Jays have opted for Eric Lauer (2-1, 2.08 ERA).

Based on the latest simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Cardinals as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Toronto-St. Louis game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Cardinals' chance of winning at 56%, with the Blue Jays at 44%."

For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Blue Jays vs. Cardinals predictions page.

Cardinals vs. Blue Jays Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Wednesday's MLB matchup between the Blue Jays and Cardinals 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Cardinals a 56% chance of beating the Blue Jays.

According to our model, the Blue Jays (+1.5) have a 63% chance of covering the run line, while the over/under total of 8.5 runs has a 51% chance of staying under.

Blue Jays vs. Cardinals Odds [6/11/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Blue Jays	Cardinals
Run Line	+1.5 (-178)	-1.5 (+150)
Moneyline	+118	-138
Total	o8.5 (-110)	u8.5 (-108)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Blue Jays vs. Cardinals Picks and Best Bets

Our model's biggest edge in today's Blue Jays vs. Cardinals matchup is on the run line.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Blue Jays vs. Cardinals Game-Day Updates and Essential Details

Wednesday's MLB action between the Cardinals and Blue Jays at Busch Stadium is scheduled to commence at 2:15PM ET.

• Who: Toronto Blue Jays vs. St. Louis Cardinals
• Date: Wednesday, June 11, 2025
• Time: 2:15PM ET/11:15AM PT
• Venue: Busch Stadium

Dimers.com's in-depth preview of Wednesday's Blue Jays vs. Cardinals matchup includes our prediction, picks and the latest betting odds.

Before making any Toronto vs. St. Louis picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
• Understand where sports odds come from and how they're applied to baseball matchups
• Learn how to use Dimers Futures to find long-term betting opportunities as the World Series draws closer
• Stay informed with where online sports betting is currently legal and which betting sites are safest to use
• Boost your success with strategies to win at sports betting and explore why MLB is one of the best leagues to bet on

Conclusion

We predict the Cardinals, with a 56% win probability, will likely beat the Blue Jays on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Blue Jays vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest predictions for the World Series, American League, National League and each division.