Jun 21, 2026
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Read Article Blue Jays vs. Cubs prediction: Why Toronto is favored to win Sunday's MLB matchup [6/21/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Toronto Blue Jays vs Chicago Cubs predictions for MLB Sunday.
The Chicago Cubs will square off with the Toronto Blue Jays, in what is expected to be a close MLB game, at Wrigley Field on Sunday, beginning at 2:20 PM ET.
Shota Imanaga (4-6, 4.26 ERA) will start on the mound for the Cubs, while the Blue Jays are going with Dylan Cease (4-3, 2.71 ERA).
Based on updated simulation results, Dimers' advanced MLB model gives the Blue Jays a slight edge with a 52.8% win probability over the Cubs.
This article offers an expanded analysis of Sunday's Blue Jays vs. Cubs matchup, including best bets and picks.
Blue Jays vs. Cubs prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the outcome of Sunday's MLB game between the Blue Jays and Cubs, forming part of our MLB predictions coverage.
Our leading predictive model currently gives the Blue Jays a 52.8% chance of beating the Cubs.
According to our model, the Cubs (+1.5) have a 60.8% chance of covering the run line, while the 6.5-run over/under has a 58.2% chance of going over,.
Blue Jays vs. Cubs odds [6/21/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Blue Jays | Cubs |
|---|---|---|
| Run Line | -1.5 (+146) | +1.5 (-170) |
| Moneyline | -120 | +106 |
| Total | o6.5 (-115) | u6.5 (-102) |
All odds are correct at the time of publication and are subject to change.
Blue Jays vs. Cubs picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Blue Jays -1.5 | +146 |
| Moneyline | Cubs | +106 |
| Total | Over 6.5 | -115 |
According to our MLB best bets, the top play to make on this game is Over 6.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Blue Jays vs. Cubs game-day updates and essential details
Sunday's MLB action between the Cubs and Blue Jays at Wrigley Field is scheduled to commence at 2:20 PM ET.
- Who: Toronto Blue Jays vs. Chicago Cubs
- Date: Sunday, June 21, 2026
- Time: 2:20 PM ET/11:20AM PT
- Venue: Wrigley Field
Conclusion
We predict the Blue Jays, with a 52.8% win probability, will likely beat the Cubs in Sunday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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