Cardinals vs. Cubs prediction: Why Cubs are favored to win Sunday's MLB matchup [7/5/2026]
Get St. Louis Cardinals vs Chicago Cubs predictions for MLB Sunday.

MLB action continues on Sunday at 2:30 PM ET as the St. Louis Cardinals square off with the Chicago Cubs at Wrigley Field.
The Cubs will start Javier Assad (6-1, 4.53 ERA), up against Matthew Liberatore (4-5, 5.34 ERA) for the Cardinals.
Based on updated simulation results, Dimers' advanced MLB model projects the Cubs as the most likely winner of the Cardinals vs. Cubs game.
This article offers an expanded analysis of Sunday's matchup, including best bets and picks.
Cardinals vs. Cubs prediction: Who will win and cover?
Our independent predictive model currently gives the Cubs a 61.0% chance of beating the Cardinals.
According to our model, the Cardinals (+1.5) have a 56.8% chance of covering the run line, while the 8-run over/under has a 51.6% chance of going over,.
Cardinals vs. Cubs odds [7/5/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Cardinals | Cubs |
|---|---|---|
| Run Line | +1.5 (-168) | -1.5 (+150) |
| Moneyline | +130 | -146 |
| Total | o8 (-110) | u8 (-110) |
All odds are correct at the time of publication and are subject to change.
Cardinals vs. Cubs picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Cubs -1.5 | +150 |
| Moneyline | Cubs | -146 |
| Total | Over 8 | -110 |
According to our MLB best bets, the top play to make on this game is Cubs -1.5 at the spread.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Cardinals vs. Cubs game-day updates and essential details
Sunday's MLB action between the Cubs and Cardinals at Wrigley Field is scheduled to commence at 2:30 PM ET.
- Who: St. Louis Cardinals vs. Chicago Cubs
- Date: Sunday, July 5, 2026
- Time: 2:30 PM ET/11:30AM PT
- Venue: Wrigley Field
Conclusion
We predict the Cubs, with a 61.0% win probability, will likely beat the Cardinals in Sunday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.



