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San Francisco 49ers vs. Philadelphia Eagles updated prediction featuring Christian McCaffrey, Saquon Barkley [Wild Card Game, 2026]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get new expert 49ers vs Eagles predictions for Sunday's game.
Dimers' latest NFL predictions are live for Philadelphia Eagles vs. San Francisco 49ers in Wild Card round of the playoffs, with our model giving the Eagles a 65% of winning.
As Sunday approaches, both teams have updated their injury reports. A few lineup decisions are still up in the air, and those could shape how each side approaches this NFC showdown.
Since our early Eagles-49ers predictions, we’ve updated the win probabilities, score projections, and TD odds for Christian McCaffrey, Saquon Barkley, and others.
For the full simulation breakdown—including spreads, totals, touchdown probabilities, and the full list of player props—check out our 49ers vs. Eagles page.
What's changed? San Francisco vs. Philadelphia updated predictions
Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Niners vs. Eagles matchup stacks up. Here are the updated forecasts:
- Straight Up Win Probabilities: 49ers 35%, Eagles 65%
- Predicted Final Score: 49ers 20-24 Eagles
- Spread: 49ers (+4.5) 54%, Eagles (-4.5) 46%
- Total Points (44.5): Over 50%, Under 50%
As of January 8, 2026, these 49ers-Eagles figures reflect changes since our early-week simulation.
Anytime touchdown scorer predictions
New NFL player projections for Wild Card Weekend highlight the top candidates to find the end zone in Niners-Eagles on Sunday:
San Francisco 49ers
- Christian McCaffrey: 58.4% probability
- George Kittle: 34.0% probability
- Jauan Jennings: 30.4% probability
Philadelphia Eagles
- Saquon Barkley: 48.1% probability
- Jalen Hurts: 42.5% probability
- A.J. Brown: 37.0% probability
Niners vs. Eagles latest odds
The best current odds from the top sportsbooks in the US:
- Spread: 49ers +4.5 (-110), Eagles -4.5 (-108)
- Moneyline: 49ers +195, Eagles -220
- Total: Over/Under 44.5 (-105/-110)
Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.
Niners vs. Eagles Wild Card Game details
Sunday's matchup between the Eagles and 49ers at Lincoln Financial Field is scheduled for January 11, 2026.
- Who: San Francisco 49ers vs. Philadelphia Eagles
- Date: Sunday, January 11, 2026
- Time: 4:30 PM ET/1:30PM PT
- Venue: Lincoln Financial Field
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Conclusion
We predict the Eagles, with a 65% win probability, will likely beat the 49ers in this NFL postseason matchup. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.
Enhanced by AI and automation, this article delivers quick, accurate insights on the 49ers vs. Eagles game, with human oversight maintaining high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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