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San Francisco 49ers vs. Philadelphia Eagles: Experts release early Wild Card Game preview [2026]
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get early predictions for the upcoming 49ers vs Eagles NFL game.
The San Francisco 49ers and Philadelphia Eagles will meet in Wild Card Weekend action at Lincoln Financial Field on Sunday, January 11, 2026, starting at 4:30 PM ET.
Early simulations from Dimers' trusted NFL model favor the Eagles as the most likely winner of this NFC matchup.
For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive 49ers vs. Eagles predictions page.
San Francisco vs. Philadelphia early predictions
Leveraging trusted machine learning and analysis, we have simulated the Niners vs. Eagles game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:
- Straight up win probabilities: 49ers 34%, Eagles 66%
- Predicted final score: 49ers 20-24 Eagles
- Spread: 49ers (+4.5) 50%, Eagles (-4.5) 50%
- Total points (44.5): Over 50%, Under 50%
As of January 5, 2026, these 49ers-Eagles figures and predictions reflect the latest data and insights available.
Niners vs. Eagles Wild Card Game details
Sunday's matchup between the Eagles and 49ers at Lincoln Financial Field is scheduled for January 11, 2026.
- Who: San Francisco 49ers vs. Philadelphia Eagles
- Date: Sunday, January 11, 2026
- Time: 4:30 PM ET/1:30PM PT
- Venue: Lincoln Financial Field
Niners vs. Eagles opening odds
We've researched the best betting odds across America for this Wild Card game, which are listed here:
- Spread: 49ers +4.5 (-110), Eagles -4.5 (-108)
- Moneyline: 49ers +190, Eagles -220
- Total: Over/Under 44.5 (-115/-105)
Odds may continue to move—track live changes via our NFL odds page.
Anytime touchdown scorer predictions
Early NFL player projections for Wild Card Weekend highlight the top candidates to score a TD in Niners-Eagles in Week 19:
San Francisco 49ers
- Christian McCaffrey: 67.7% probability
- George Kittle: 38.6% probability
- Jauan Jennings: 36.8% probability
Philadelphia Eagles
- Saquon Barkley: 46.4% probability
- Jalen Hurts: 46.2% probability
- A.J. Brown: 39.3% probability
49ers vs Eagles player props
Christian McCaffrey is projected to lead rushing for the 49ers, while Saquon Barkley is expected to pace the Eagles on the ground.
In the receiving game, our projections favor San Francisco's George Kittle and Philadelphia's A.J. Brown as the likely leaders for each team.
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Conclusion
We predict the Eagles, with a 66% win probability, will likely beat the 49ers in this NFL postseason matchup. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.
Enhanced by AI and automation, this article delivers quick, accurate insights on the 49ers vs. Eagles game, with human oversight maintaining high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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More on NFL
Stay up-to-date with the latest NFL betting news and data-driven parlay picks all season long. Plus, our Super Bowl odds for top predictions and the best available odds on the Super Bowl, AFC, NFC and each division.
Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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