Padres vs. Giants Prediction: San Francisco Predicted to Win Monday's MLB Matchup [6/2/2025]

The San Francisco Giants and San Diego Padres are scheduled to meet in MLB action at Oracle Park on Monday, starting at 9:45PM ET.

The Giants will have Logan Webb (5-5, 2.82 ERA) as their starting pitcher, while the Padres are going with Stephen Kolek (3-1, 4.11 ERA).

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Giants as the most likely winner of today's game.

"Our team has utilized the latest data to simulate Monday's San Diego-San Francisco game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Incorporating recent updates and thousands of additional inputs, our prediction shows the Giants are likely to win, with a probability of 57%, compared to the Padres' 43%."

For expanded analysis of Monday's matchup, including best bets and picks, visit our interactive Padres vs. Giants predictions page.

Giants vs. Padres Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Monday's MLB matchup between the Padres and Giants 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Giants a 57% chance of beating the Padres.

According to our model, the Padres (+1.5) have a 63% chance of covering the run line, while the over/under total of 7.5 runs has an equal 50-50 chance of hitting.

Padres vs. Giants Odds [6/2/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Padres	Giants
Run Line	+1.5 (-142)	-1.5 (+125)
Moneyline	+150	-174
Total	o7.5 (+100)	u7.5 (-120)

All odds are correct at the time of publication and are subject to change.

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Padres vs. Giants Picks and Best Bets

Our model's strongest edge in today's Padres vs. Giants matchup is on the over/under.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Padres vs. Giants Game-Day Updates and Essential Details

Monday's MLB game between the Giants and Padres at Oracle Park is scheduled to commence at 9:45PM ET.

• Who: San Diego Padres vs. San Francisco Giants
• Date: Monday, June 2, 2025
• Time: 9:45PM ET/6:45PM PT
• Venue: Oracle Park

Dimers.com's comprehensive preview of Monday's Padres vs. Giants matchup includes our prediction, picks and the latest betting odds.

Before making any San Diego vs. San Francisco picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Giants, with a 57% win probability, will likely beat the Padres on Monday.

AI and automation have enhanced this article to quickly deliver accurate Padres vs. Giants insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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