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Purdue vs. Indiana CFB Prediction and Odds - Nov 26, 2022

Indiana takes on the favored Purdue in College Football action at Memorial Stadium on Saturday, starting at 3:30PM ET.

Dimers' best betting picks for Purdue vs. Indiana, plus game predictions and betting odds, are featured in this article.


Who will win Purdue vs. Indiana?

Based on high-tech machine learning and data, Dimers.com has simulated Purdue vs. Indiana 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, currently gives Purdue a 74% chance of defeating Indiana.

More: Full Betting Guide for Purdue vs. Indiana

Purdue vs. Indiana Game Odds

  • Spread: Indiana +10 (-105), Purdue -10 (-110)
  • Moneyline: Indiana +315, Purdue -370
  • Total: Over/Under 52.5 (-115/-105)

Point Spread, Moneyline and Over/Under

Indiana is listed as the +10 underdog against Purdue, with -105 at PointsBet the best odds currently available.

For the favored Purdue (-10) to cover the spread, Caesars Sportsbook has the best odds currently on offer at -110.

FanDuel Sportsbook currently has the best moneyline odds for Indiana at +315, which means you can throw down $100 to profit $315, earning a total payout of $415, if it wins.

Elsewhere, Caesars Sportsbook currently has the best moneyline odds for Purdue at -370, where you can risk $370 to win $100, for a total payout of $470, if it comes out on top.

The Over/Under for total points scored sits at 52.5 with PointsBet, which currently has the best odds for the Over at -115, as well as the best odds for the Under at -105.

As always, check out the sportsbooks you have access to in your state for the best College Football odds and lines.

According to DimersBOT, Purdue (-10) is a 52% chance of covering the spread, while the Over/Under total of 52.5 points is a 52% chance of going Over.

More: Best Free Bet Tracker

Best Bets for Purdue vs. Indiana


Our best bets are based on world-class simulations and wagering expertise to help you make more informed investments with your state's legal sportsbooks.

While Purdue is more likely to win the game, according to DimersBOT, taking Indiana moneyline is the best option because of the edge identified when comparing our data-led probabilities to the sportsbooks' odds currently on offer.

Taking advantage of the edges published on Dimers.com is one of the keys to being profitable in the long run.

Purdue vs. Indiana Prediction

Dimers.com's predicted final score for Purdue vs. Indiana at Memorial Stadium on Saturday has Purdue winning 31-21.

Click or tap on See Matchup for more.


Dimers has full betting coverage of this week's Purdue-Indiana matchup, including pregame predictions, free betting picks, and live win probabilities.

Remember, DimersBOT updates often, so keep an eye on this page for any changes to our betting analysis before Purdue vs. Indiana on Saturday November 26, 2022.


Purdue vs. Indiana 2022 CFB Game Info

Saturday's matchup between Indiana and Purdue in College Football at Memorial Stadium is scheduled to start at 3:30PM ET.

  • Who: Purdue vs. Indiana
  • Date: Saturday November 26, 2022
  • Time: 3:30PM ET / 12:30PM PT
  • Venue: Memorial Stadium

Want to join an online sportsbook and start betting on College Football today? We've reviewed the best available sign-up offers for every legal betting state.

What CFB games are on this week?

Purdue and Indiana aren't the only two NCAA Football teams you can bet on. DimersBOT never stops and we've got picks and best bets for every single CFB game via our College Football Predictions section.

Not only do we provide with you great predictions, but we also have recommended bets for the Spread, Over/Under and Moneyline. Sound good? Hell yeah it does!

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