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76ers vs. Bulls prediction: Why Philadelphia is favored to win Friday's NBA matchup [12/26/2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Philadelphia 76ers vs Chicago Bulls predictions for NBA Friday.
The Chicago Bulls and Philadelphia sixers are scheduled to meet in NBA action at United Center on Friday, starting at 7:30 PM ET.
Based on updated simulations and today’s injury news, Dimers' advanced NBA model predicts the 76ers as the most likely winner of the 76ers vs. Bulls game.
This prediction follows the latest NBA Injury Report, which suggests the Bulls lineup will feature players like Coby White, Josh Giddey and Nikola Vucevic, while the 76ers will rely on Tyrese Maxey, Joel Embiid and Paul George.
This article offers further insights into Friday's matchup, including an expanded look at the predicted score, best bets and player prop picks.
Sixers vs. Sixers prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the result of Friday's NBA game between the 76ers and Bulls 10,000 times as part of our NBA predictions coverage.
Our leading predictive model gives the 76ers a 58% chance of beating the Bulls. Our predicted final score has the 76ers winning 121-119.
According to our model, the bookmakers have got it right, and the 76ers and Bulls each have a 50% chance of covering the spread, while the over/under total of 241.5 points has a 53% chance of staying under.
76ers vs. Bulls odds
We have researched the best NBA odds in America for this game, which are listed here:
| Bet Type | 76ers | Bulls |
|---|---|---|
| Spread | -1.5 (-110) | +1.5 (-108) |
| Moneyline | -125 | +116 |
| Total | o241.5 (-106) | u241.5 (-110) |
All odds are correct at the time of publication and are subject to change.
76ers vs. Bulls picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | 76ers -1.5 | -110 |
| Moneyline | 76ers | -125 |
| Total | Under 241.5 | -110 |
According to our best NBA bets for Friday, the top play to make on this game is Under 241.5 total points.
76ers vs. Bulls player props
NBA player props are an exciting way to wager on the Philadelphia vs. Chicago game without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at United Center.
Tyrese Maxey is expected to lead the 76ers with 28 points, 4 rebounds and 7 assists, while Coby White is projected to have 21 points, 4 rebounds and 5 assists for the Bulls.
Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.
76ers prediction
Our model's projected player stats for the 76ers are:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Tyrese Maxey | 28 | 4 | 7 | 3 | 51 |
| Joel Embiid | 25 | 8 | 4 | 2 | 48 |
| Paul George | 17 | 5 | 4 | 3 | 37 |
| VJ Edgecombe | 15 | 5 | 4 | 2 | 33 |
| Quentin Grimes | 14 | 3 | 4 | 2 | 28 |
Bulls prediction
Projected points, rebounds, assists and three-pointers made for the Bulls:
| Player | PTS | REB | AST | 3PM | DFS |
|---|---|---|---|---|---|
| Coby White | 21 | 4 | 5 | 3 | 37 |
| Josh Giddey | 19 | 9 | 10 | 2 | 51 |
| Nikola Vucevic | 17 | 9 | 3 | 2 | 38 |
| Matas Buzelis | 14 | 5 | 2 | 2 | 28 |
| Kevin Huerter | 10 | 3 | 2 | 2 | 21 |
Sixers vs. Bulls game-day updates and essential details
Friday's game between the Bulls and 76ers at United Center is scheduled to begin at 7:30 PM ET.
- Who: Philadelphia 76ers vs. Chicago Bulls
- Date: Friday, December 26, 2025
- Time: 7:30 PM ET/4:30PM PT
- Venue: United Center
Conclusion
We predict the 76ers, with a 58% win probability, will likely beat the Bulls on Friday, with Josh Giddey projected for a game-high 51 fantasy points.
AI and automation have enhanced this article to quickly deliver accurate 76ers vs. Bulls insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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